Now showing items 2-2 of 2

    • Molecular Mechanisms of Disease Pathogenesis Differ in Krabbe Disease Variants 

      Spratley, Samantha; Hill, Chris; Viuff, Agnete; Edgar, James; Skjodt, Karsten; Deane, Janet (Wiley, 2016)
      Krabbe disease is a severe, fatal neurodegenerative disorder caused by defects in the lysosomal enzyme galactocerebrosidase (GALC). The correct targeting of GALC to the lysosome is essential for the degradation of ...