Browsing by Author "Huang, Ni"

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The functional impact of copy number variation in the human genome

Huang, Ni (2012-03-06)

Copy number variation (CNV) is a class of genetic variation where large segments of the genome vary in copy number among different individuals. It has become clear in the past decade that CNV affects a significant proportion ...
Stable $\textit{Caenorhabditis elegans}$ chromatin domains separate broadly expressed and developmentally regulated genes

Evans, Kenneth J.; Huang, Ni; Stempor, Przemyslaw; Chesney, Michael A.; Down, Thomas A.; Ahringer, Julie (National Academy of Sciences, 2016-10-25)

Eukaryotic genomes are organized into domains of differing structure and activity. There is evidence that the domain organization of the genome regulates its activity, yet our understanding of domain properties and the ...