Now showing items 2-3 of 3

    • MMP1 bimodal expression and differential response to inflammatory mediators is linked to promoter polymorphisms 

      Affara, Muna; Dunmore, Benjamin J.; Sanders, Deborah A.; Johnson, Nicola; Print, Cristin G.; Charnock-Jones, D. Stephen (2011-01-19)
      Abstract Background Identifying the functional importance of the millions of single nucleotide polymorphisms (SNPs) in the human genome is a difficult challenge. Therefore, a reverse strategy, which identifies functionally ...
    • Performance of automated scoring of ER, PR, HER2, CK5/6 and EGFR in breast cancer tissue microarrays in the Breast Cancer Association Consortium 

      Howat, William; Blows, Fiona; Provenzano, Elena; Brook, Mark; Morris, Lorna; Gazinska, Patrycja; Johnson, Nicola et al. (Wiley, 2014-12-04)
      Breast cancer risk factors and clinical outcomes vary by tumor marker expression. However, individual studies often lack the power required to assess these relationships, and large-scale analyses are limited by the need ...