Now showing items 1-3 of 3

    • Appraising the relevance of DNA copy number loss and gain in prostate cancer using whole genome DNA sequence data. 

      Camacho, Niedzica; Van Loo, Peter; Edwards, Sandra; Kay, Jonathan D; Matthews, Lucy; Haase, Kerstin; Clark, Jeremy et al. (Public Library of Science (PLoS), 2017-09-25)
      A variety of models have been proposed to explain regions of recurrent somatic copy number alteration (SCNA) in human cancer. Our study employs Whole Genome DNA Sequence (WGS) data from tumor samples (n = 103) to comprehensively ...
    • Climate Code Foundation 

      Barnes, Nick; Jones, David (Murray-Rust group, Unilever Centre for Molecular Science Informatics, Department of Chemistry, University of Cambridge, 2011-07-05)
      Climate Code Foundation - who are we? A non-profit organisation founded in August 2010; our goal is to promote the public understanding of climate science, by increasing the visibility and clarity of the software used in ...
    • A comprehensive assessment of somatic mutation detection in cancer using whole genome sequencing 

      Alioto, Tyler S; Buchhalter, Ivo; Derdak, Sophia; Hutter, Barbara; Eldridge, Matthew D; Hovig, Eivind; Heisler, Lawrence E et al. (Nature Publishing Group, 2015)
      As whole-genome sequencing for cancer genome analysis becomes a clinical tool, a full understanding of the variables affecting sequencing analysis output is required. Here using tumour-normal sample pairs from two different ...