Now showing items 4-6 of 6

    • A selective sweep on a deleterious mutation in the CPT1A gene in Arctic populations 

      Clemente, Florian J.; Cardona, Alexia; Inchley, Charlotte E.; Peter, Benjamin M.; Jacobs, Guy; Pagani, Luca; Lawson, Daniel J. et al. (Elsevier, 2014-10-23)
      Arctic populations live in an environment characterized by extreme cold and the absence of plant foods for much of the year, and are likely to have undergone genetic adaptations to these environmental conditions in the ...
    • Selective sweep on human amylase genes postdates the split with Neanderthals 

      Inchley, Charlotte; Larbey, Cynthia; Shwan, NAA; Pagani, L; Saag, L; Antão, T; Jacobs, G et al. (Nature Publishing Group, 2016-11-17)
      Humans have more copies of amylase genes than other primates. It is still poorly understood, however, when the copy number expansion occurred and whether its spread was enhanced by selection. Here we assess amylase copy ...
    • Validity of visceral adiposity estimates from DXA against MRI in Kuwaiti men and women. 

      Mohammad, A; De Lucia Rolfe, Emanuella; Sleigh, Alison; Kivisild, Toomas; Behbehani, K; Wareham, Nicholas John; Brage, Soren et al. (Nature Publishing Group, 2017-01-09)
      ${\bf Objectives:}$ The prevalence of obesity and diabetes in the Middle East is amongst the highest in the world. Valid measures of abdominal adiposity are essential to understanding the metabolic consequences of obesity. ...