Now showing items 6-6 of 6

    • Promoter-bound METTL3 maintains myeloid leukaemia by m6A-dependent translation control. 

      Barbieri, Isaia; Tzelepis, Konstantinos; Pandolfini, Luca; Shi, Junwei; Millán-Zambrano, Gonzalo; Robson, Samuel C; Aspris, Demetrios et al. (Springer Nature, 2017-12)
      N6-methyladenosine (m6A) is an abundant internal RNA modification in both coding and non-coding RNAs, catalysed by the METTL3/METTL14 methyltransferase complex. Here we define a novel pathway specific for METTL3, implicated ...