Browsing by Author "Leigh, James A"

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    • Defining the ABC of gene essentiality in streptococci 

      Charbonneau, Amelia RL; Forman, Oliver P; Cain, Amy K; Newland, Graham; Robinson, Carl; Boursnell, Mike; Parkhill, Julian et al. (2017-05-31)

    • Defining the ABC of gene essentiality in streptococci 

      Charbonneau, Amelia RL; Forman, Oliver P; Cain, Amy K; Newland, Graham; Robinson, Carl; Boursnell, Mike; Parkhill, Julian et al. (2017-05-31)
      Abstract Background Utilising next generation sequencing to interrogate saturated bacterial mutant libraries provides unprecedented information for the assignment of genome-wide ...

    • Evidence for niche adaptation in the genome of the bovine pathogen Streptococcus uberis 

      Ward, Philip N; Holden, Matthew TG; Leigh, James A; Lennard, Nicola; Bignell, Alexandra; Barron, Andy; Clark, Louise et al. (2009-01-28)
      Abstract Background Streptococcus uberis, a Gram positive bacterial pathogen responsible for a significant proportion of bovine mastitis in commercial dairy herds, colonises multiple body sites of the cow including the ...