Now showing items 2-8 of 8

    • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) 

      Klionsky, Daniel J; Abdelmohsen, Kotb; Abe, Akihisa; Abedin, Md Joynal; Abeliovich, Hagai; Arozena, Abraham Acevedo; Adachi, Hiroaki et al. (Taylor & Francis, 2016-01-21)
    • Identification of rare sequence variation underlying heritable pulmonary arterial hypertension. 

      Gräf, Stefan Andreas; Haimel, Matthias; Bleda, Marta; Hadinnapola, Charaka Mayura; Southgate, Laura; Li, Wei; Hodgson, Joshua et al. (Springer Nature, 2018-04-12)
      Pulmonary arterial hypertension (PAH) is a rare disorder with a poor prognosis. Deleterious variation within components of the transforming growth factor-β pathway, particularly the bone morphogenetic protein type 2 receptor ...
    • Porcine transcriptome analysis based on 97 non-normalized cDNA libraries and assembly of 1,021,891 expressed sequence tags 

      Gorodkin, Jan; Cirera, Susanna; Hedegaard, Jakob; Gilchrist, Michael J.; Panitz, Frank; Jorgensen, Claus B.; Scheibye-Knudsen, Karsten et al. (2007-04-02)
      Background Knowledge of the structure of gene expression is essential for mammalian transcriptomics research. We analyzed a collection of more than one million porcine expressed sequence tags (ESTs), of which two-thirds ...
    • The Prodomain-bound Form of Bone Morphogenetic Protein 10 Is Biologically Active on Endothelial Cells 

      Jiang, He; Salmon, Richard Michael; Upton, Paul David; Wei, Zhenquan; Lawera, Aleksandra; Davenport, Anthony Peter; Morrell, Nicholas et al. (American Society for Biochemistry and Molecular Biology, 2015-12-02)
      BMP10 is highly expressed in the developing heart and plays essential roles in cardiogenesis. BMP10 deletion in mice results in embryonic lethality because of impaired cardiac development. In adults, BMP10 expression is ...
    • Regulation of Bone Morphogenetic Protein 9 by Redox-Dependent Proteolysis 

      Wei, Zhenquan; Salmon, Richard Michael; Upton, Paul David; Morrell, Nicholas; Li, Wei (American Society for Biochemistry and Molecular Biology, 2014-09-18)
      BMP9, a member of the TGFβ superfamily, is a homodimer that forms a signaling complex with two type I and two type II receptors. Signaling through high-affinity activin receptor-like kinase 1 (ALK1) in endothelial cells, ...
    • Regulation of the ALK1 ligands, BMP9 and BMP10 

      Li, Wei; Salmon, Richard Michael; Jiang, He; Morrell, Nicholas (2016-08-14)
      Bone morphogenetic protein (BMP)9 and BMP10 are high affinity ligands for activin receptor-like kinase 1 (ALK1), a type I BMP receptor mainly expressed on vascular endothelial cells. ALK1-mediated BMP9/BMP10 signalling ...
    • Research data supporting the conference paper 'Monitoring on the performance of temporary props using wireless strain sensing', submitted by David Rodenas-Herraiz. 

      Xu, Xiaomin M; Fidler, Paul Ronald; Rodenas-Herraiz, David; Li, Wei; Kumar, Varindra; Birks, Jules; Yan, Jize et al.