Now showing items 3-4 of 4

    • Mutational spectrum in a worldwide study of 29,700 families with BRCA1 or BRCA2 mutations. 

      Rebbeck, Timothy R; Friebel, Tara M; Friedman, Eitan; Hamann, Ute; Huo, Dezheng; Kwong, Ava; Olah, Edith et al. (Wiley-Blackwell, 2018-05)
      The prevalence and spectrum of germline mutations in BRCA1 and BRCA2 have been reported in single populations, with the majority of reports focused on Caucasians in Europe and North America. The Consortium of Investigators ...
    • Prevalence and Penetrance of Major Genes and Polygenes for Colorectal Cancer. 

      Win, Aung Ko; Jenkins, Mark A; Dowty, James G; Antoniou, Antonis; Lee, Andrew John; Giles, Graham G; Buchanan, Daniel D et al. (American Association for Cancer Research, 2017-03)
      BACKGROUND: While high-risk mutations in identified major susceptibility genes (DNA mismatch repair genes and MUTYH) account for some familial aggregation of colorectal cancer, their population prevalence and the causes ...