Browsing by Author "Liu, Bin"

Now showing items 2-5 of 5

    • Identification of rare sequence variation underlying heritable pulmonary arterial hypertension. 

      Gräf, Stefan Andreas; Haimel, Matthias; Bleda, Marta; Hadinnapola, Charaka Mayura; Southgate, Laura; Li, Wei; Hodgson, Joshua et al. (Springer Nature, 2018-04-12)
      Pulmonary arterial hypertension (PAH) is a rare disorder with a poor prognosis. Deleterious variation within components of the transforming growth factor-β pathway, particularly the bone morphogenetic protein type 2 receptor ...

    • Porcine transcriptome analysis based on 97 non-normalized cDNA libraries and assembly of 1,021,891 expressed sequence tags 

      Gorodkin, Jan; Cirera, Susanna; Hedegaard, Jakob; Gilchrist, Michael J.; Panitz, Frank; Jorgensen, Claus B.; Scheibye-Knudsen, Karsten et al. (2007-04-02)
      Background Knowledge of the structure of gene expression is essential for mammalian transcriptomics research. We analyzed a collection of more than one million porcine expressed sequence tags (ESTs), of which two-thirds ...

    • Research data supporting "Crowdsourcing the General Public for Large Scale Molecular Pathology Studies in Cancer" 

      Candido do Reis, Francisco J.; Lynn, Stuart; Ali, H. Raza; Eccles, Diana; Hanby, Andrew; Provenzano, Elena; Caldas, Carlos et al. (2015-05-08)

    • The somatic mutation profiles of 2,433 breast cancers refine their genomic and transcriptomic landscapes 

      Pereira, Bernard; Chin, Suet Feung; Rueda, Oscar M; Vollan, Hans-Kristian Moen; Provenzano, Elena; Bardwell, Helen A; Pugh, Michelle et al. (Nature Publishing Group, 2016-05-10)
      The genomic landscape of breast cancer is complex, and inter- and intra-tumour heterogeneity are important challenges in treating the disease. In this study, we sequence 173 genes in 2,433 primary breast tumours that have ...