Now showing items 1-2 of 2

    • Early-life nutrition modulates the epigenetic state of specific rDNA genetic variants in mice 

      Holland, Michelle L.; Lowe, Robert; Caton, Paul W.; Gemma, Carolina; Carbajosa, Guillermo; Danson, Amy F.; Carpenter, Asha A. M. et al. (American Association for the Advancement of Science, 2016-07-07)
      A suboptimal early-life environment, due to poor nutrition or stress during pregnancy, can influence lifelong phenotypes in the progeny. Epigenetic factors are thought to be key mediators of these effects. We show that ...
    • Predicting the mechanism of phospholipidosis 

      Lowe, Robert; Mussa, Hamse Y; Nigsch, Florian; Glen, Robert C; Mitchell, John BO (2012-01-26)
      Abstract The mechanism of phospholipidosis is still not well understood. Numerous different mechanisms have been proposed, varying from direct inhibition of the breakdown of phospholipids to the binding of a drug compound ...