Now showing items 26-45 of 60

    • Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation 

      Ghoussaini, Maya; Edwards, Stacey L; Michailidou, Kyriaki; Nord, Silje; Cowper-Sal•lari, Richard; Desai, Kinjal; Kar, Siddhartha et al. (2014-09-23)
    • Flavonoid Intake in European Adults (18 to 64 Years) 

      Vogiatzoglou, Anna; Mulligan, Angela Assumpta; Lentjes, Maria Antonetta; Luben, Robert; Spencer, Jeremy PE; Schroeter, Hagen; Khaw, Kay-Tee et al. (2015-05-26)
    • Fracture Risk in Relation to Serum 25-Hydroxyvitamin D and Physical Activity: Results from the EPIC-Norfolk Cohort Study. 

      Julian, C; Lentjes, Maria Antonetta; Huybrechts, I; Luben, Robert; Wareham, Nicholas John; Moreno, LA; Khaw, Kay-Tee (PLOS, 2016-11-23)
      Vitamin D deficiency and physical inactivity have been associated with bone loss and fractures, but their combined effect has scarcely been studied either in younger or older adults. Therefore, we aimed to assess the ...
    • Genetic determinants of heel bone properties: Genome-wide association meta-analysis and replication in the GEFOS/GENOMOS consortium 

      Moayyeri, Alireza; Hsu, Yi-Hsiang; Karasik, David; Estrada, Karol; Xiao, Su-Mei; Nielson, Carrie; Srikanth, Priya et al. (2014-01-14)
    • Genetic modifiers of CHEK2*1100delC-associated breast cancer risk 

      Muranen, Taru A; Greco, Dario; Blomqvist, Carl; Aittomäki, Kristiina; Khan, Sofia; Hogervorst, Frans; Verhoef, Senno et al. (2016-10-06)
      PURPOSE: CHEK2*1100delC is a founder variant in European populations that confers a two- to threefold increased risk of breast cancer (BC). Epidemiologic and family studies have suggested that the risk associated with ...
    • Genetically Predicted Body Mass Index and Breast Cancer Risk: Mendelian Randomization Analyses of Data from 145,000 Women of European Descent 

      Guo, Yan; Andersen, Shaneda Warren; Shu, Xiao-Ou; Michailidou, Kyriaki; Bolla, Manjeet K; Wang, Qin; Garcia-Closas, Montserrat et al. (2016-08-23)
    • Genome-wide analysis identifies 12 loci influencing human reproductive behavior. 

      Barban, N; Jansen, R; de, Vlaming R; Vaez, A; Mandemakers, JJ; Tropf, FC; Shen, X et al. (Nature Publishing Group, 2016-10-31)
      The genetic architecture of human reproductive behavior-age at first birth (AFB) and number of children ever born (NEB)-has a strong relationship with fitness, human development, infertility and risk of neuropsychiatric ...
    • Genome-wide association reveals that common genetic variation in the kallikrein-kinin system is associated with serum L-arginine levels 

      Zhang, W; Jernerén, F; Lehne, BC; Chen, M-H; Luben, Robert; Johnston, C; Elshorbagy, A et al. (Schattauer, 2016-11-30)
      L-arginine is the essential precursor of nitric oxide, and is involved in multiple key physiological processes, including vascular and immune function. The genetic regulation of blood L-arginine levels is largely unknown. ...
    • Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits 

      Justice, AE; Winkler, TW; Feitosa, MF; Graff, M; Fisher, VA; Young, K; Barata, L et al. (Nature Publishing Group, 2017-04-26)
      Few genome-wide association studies (GWAS) account for environmental exposures, like smoking, potentially impacting the overall trait variance when investigating the genetic contribution to obesity-related traits. Here, ...
    • Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults. 

      Graff, Mariaelisa; Scott, Robert A; Justice, Anne E; Young, Kristin L; Feitosa, Mary F; Barata, Llilda; Winkler, Thomas W et al. (2017-04-27)
    • Greater accordance with the DASH dietary pattern is associated with lower diet-related greenhouse gas production but higher dietary costs in the United Kingdom 

      Monsivais, Pablo; Scarborough, Peter; Lloyd, Tina; Mizdrak, Anja; Luben, Robert; Mulligan, Angela Assumpta; Wareham, Nicholas John et al. (2015-04-29)
    • Habitual chocolate consumption and the risk of incident heart failure among healthy men and women 

      Kwok, Chun Shing; Loke, Yoon K; Welch, Ailsa A; Luben, Robert; Lentjes, Maria Antonetta; Boekholdt, S Matthijs; Pfister, Roman et al. (2016-01-28)
    • Ideal cardiovascular health and risk of cardiovascular events in the EPIC-Norfolk prospective population study 

      Lachman, Sangeeta; Peters, Ron JG; Lentjes, Maria Antonetta; Mulligan, Angela Assumpta; Luben, Robert; Wareham, Nicholas John; Khaw, Kay-Tee et al. (2015-09-02)
    • Influence of Inflammatory Polyarthritis on Quantitative Heel Ultrasound Measurements 

      Pye, Stephen R; Marshall, Tarnya; Gaffney, Karl; Luben, Robert; Khaw, Kay-Tee; Silman, Alan J; Symmons, Deborah PM et al. (2012-07-26)
    • Longitudinal association of C-reactive protein and Haemoglobin A1c over 13 years: the European Prospective Investigation into Cancer - Norfolk study 

      Ahmadi-Abhari, Sara; Kaptoge, Stephen Kipkemoi; Luben, Robert; Wareham, Nicholas John; Khaw, Kay-Tee (2015-05-22)
    • Longitudinal associations between marine omega-3 supplement users and Coronary Heart Disease in a UK population-based cohort 

      Lentjes, Maria Antonetta; Keogh, RH; Welch, AA; Mulligan, Angela Assumpta; Luben, Robert; Wareham, Nicholas John; Khaw, Kay-Tee (BMJ Journals, 2017-10-01)
      Objectives: Assess the association between marine omega-3 polyunsaturated fatty acid (n 3 PUFA) intake from supplements, mainly cod liver oil, and coronary heart disease (CHD) mortality. Design: Prospective cohort study, ...
    • No evidence that protein truncating variants in BRIP1 are associated with breast cancer risk: implications for gene panel testing 

      Easton, Douglas Frederick; Lesueur, Fabienne; Decker, Brennan; Michailidou, Kyriaki; Li, Jun; Allen, Jamie; Luccarini, Craig et al. (2016-02-26)
    • Novel associations between common breast cancer susceptibility variants and risk-predicting mammographic density measures 

      Stone, Jennifer; Thompson, Deborah Jane; dos, Santos Silva Isabel; Scott, Christopher; Tamimi, Rulla M; Lindstrom, Sara; Kraft, Peter et al. (2015-04-10)
    • Objective Sedentary Time, Moderate-to-Vigorous Physical Activity, and Physical Capability in a British Cohort 

      Keevil, Victoria Louise; Cooper, Andrew JM; Wijndaele, Katrien Lieve; Luben, Robert; Wareham, Nicholas John; Brage, Soren; Khaw, Kay-Tee (2016-03-01)
    • Omega-6 Fatty Acid Biomarkers and Incident Type 2 Diabetes: A Pooled Analysis of 20 Cohort Studies 

      Wu, JHY; Marklund, M; Imamura, Fumiaki; et al,; Forouhi, Nita Gandhi; Luben, Robert; Khaw, KT et al.
      BACKGROUND: Metabolic effects of omega-6 polyunsaturated fatty acids (n-6 PUFA) remain contentious, and evidence is limited regarding their potential role in primary prevention of type 2 diabetes (T2D). METHODS: Global ...