Now showing items 45-64 of 67

    • Large meta-analysis of genome-wide association studies identifies five loci for lean body mass. 

      Zillikens, M Carola; Demissie, Serkalem; Hsu, Yi-Hsiang; Yerges-Armstrong, Laura M; Chou, Wen-Chi; Stolk, Lisette; Livshits, Gregory et al. (2017-07-19)
    • Longitudinal association of C-reactive protein and Haemoglobin A1c over 13 years: the European Prospective Investigation into Cancer - Norfolk study 

      Ahmadi-Abhari, Sara; Kaptoge, Stephen Kipkemoi; Luben, Robert; Wareham, Nicholas John; Khaw, Kay-Tee (2015-05-22)
    • Longitudinal associations between marine omega-3 supplement users and Coronary Heart Disease in a UK population-based cohort 

      Lentjes, Maria Antonetta; Keogh, RH; Welch, AA; Mulligan, Angela Assumpta; Luben, Robert; Wareham, Nicholas John; Khaw, Kay-Tee (BMJ Journals, 2017-10-01)
      Objectives: Assess the association between marine omega-3 polyunsaturated fatty acid (n 3 PUFA) intake from supplements, mainly cod liver oil, and coronary heart disease (CHD) mortality. Design: Prospective cohort study, ...
    • No evidence that protein truncating variants in BRIP1 are associated with breast cancer risk: implications for gene panel testing 

      Easton, Douglas Frederick; Lesueur, Fabienne; Decker, Brennan; Michailidou, Kyriaki; Li, Jun; Allen, Jamie; Luccarini, Craig et al. (BMJ Group, 2016-02-26)
      Background BRCA1 interacting protein C-terminal helicase 1 (BRIP1) is one of the Fanconi Anaemia Complementation (FANC) group family of DNA repair proteins. Biallelic mutations in BRIP1 are responsible for FANC group J, and ...
    • Novel associations between common breast cancer susceptibility variants and risk-predicting mammographic density measures 

      Stone, Jennifer; Thompson, Deborah Jane; dos, Santos Silva Isabel; Scott, Christopher; Tamimi, Rulla M; Lindstrom, Sara; Kraft, Peter et al. (2015-04-10)
    • Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. 

      Dastani, Zari; Hivert, Marie-France; Timpson, Nicholas; Perry, John Richard; Yuan, Xin; Scott, Robert; Henneman, Peter et al. (2012-01)
    • Objective Sedentary Time, Moderate-to-Vigorous Physical Activity, and Physical Capability in a British Cohort 

      Keevil, Victoria Louise; Cooper, Andrew JM; Wijndaele, Katrien Lieve; Luben, Robert; Wareham, Nicholas John; Brage, Soren; Khaw, Kay-Tee (Wolters Kluwer, 2016-03-01)
      $\textbf{Purpose:}$ Sedentariness has been proposed as an independent risk factor for poor health. However, few studies have considered associations of sedentary time (ST) with physical functional health independent of ...
    • Omega-6 fatty acid biomarkers and incident type 2 diabetes: pooled analysis of individual-level data for 39 740 adults from 20 prospective cohort studies 

      Wu, JHY; Marklund, M; Imamura, Fumiaki; et al,; Forouhi, Nita Gandhi; Luben, Robert; Khaw, Kay-Tee et al. (Elsevier, 2017-12-01)
      BACKGROUND: Metabolic effects of omega-6 polyunsaturated fatty acids (n-6 PUFA) remain contentious, and evidence is limited regarding their potential role in primary prevention of type 2 diabetes (T2D). METHODS: Global ...
    • Polymorphisms in a Putative Enhancer at the 10q21.2 Breast Cancer Risk Locus Regulate NRBF2 Expression 

      Darabi, Hatef; McCue, Karen; Beesley, Jonathan; Michailidou, Kyriaki; Nord, Silje; Kar, Siddhartha; Humphreys, Keith et al. (2015-06-11)
    • Predicting admissions and time spent in hospital over a decade in a population-based record linkage study: the EPIC-Norfolk cohort 

      Luben, Robert; Hayat, Shabina Anwar; Wareham, Nicholas John; Khaw, Kay-Tee (2016-01-20)
    • RAD51B in Familial Breast Cancer 

      Pelttari, Liisa M; Khan, Sofia; Vuorela, Mikko; Kiiski, Johanna I; Vilske, Sara; Nevanlinna, Viivi; Ranta, Salla et al. (PLOS, 2016-05-05)
      Common variation on 14q24.1, close to RAD51B, has been associated with breast cancer: rs999737 and rs2588809 with the risk of female breast cancer and rs1314913 with the risk of male breast cancer. The aim of this study ...
    • Rare, protein-truncating variants in $\textit{ATM}$, $\textit{CHEK2}$ and $\textit{PALB2}$, but not $\textit{XRCC2}$, are associated with increased breast cancer risks 

      Decker, B; Allen, J; Luccarini, C; Pooley, Karen Anne; Shah, Mitulkumar Nandlal; Bolla, MK; Wang, Qin et al.
      BACKGROUND: Breast cancer (BC) is the most common malignancy in women and has a major heritable component. The risks associated with most rare susceptibility variants are not well estimated. To better characterise the ...
    • The relationship between dietary magnesium intake, stroke and its major risk factors, blood pressure and cholesterol, in the EPIC-Norfolk cohort 

      Bain, Lucy KM; Myint, Phyo K; Jennings, Amy; Lentjes, Maria Antonetta; Luben, Robert; Khaw, Kay-Tee; Wareham, Nicholas John et al. (2015-05-31)
    • Retinal Nerve Fiber Layer Measures and Cognitive Function in the EPIC-Norfolk Cohort Study 

      Khawaja, Anthony P; Chan, Michelle PY; Yip, Jennifer LY; Broadway, David C; Garway-Heath, David F; Luben, Robert; Hayat, Shabina Anwar et al. (2016-04)
    • Self-reported parkinsonian symptoms in the EPIC-Norfolk cohort 

      Ishihara, Lianna S; Khaw, Kay-Tee; Luben, Robert; Bingham, Sheila; Welch, Ailsa; Day, Nicholas E; Brayne, Carol Elspeth (2005-08-24)
      Abstract Background Parkinsonian symptoms have been associated with increased morbidity and mortality. Several studies have reported on the prevalence of signs and symptoms. Symptoms questionnaires can identify potential ...
    • Serum carbon and nitrogen stable isotopes as potential biomarkers of dietary intake and their relation with incident type 2 diabetes: the EPIC-Norfolk study 

      Patel, Pinal S; Cooper, Andrew John; O’Connell, Tamsin C; Kuhnle, Gunter GC; Kneale, Catherine K; Mulligan, Angela Assumpta; Luben, Robert et al. (American Society for Nutrition, 2014-07-02)
      Background - Stable-isotope ratios of carbon (13C/12C, expressed as δ13C) and nitrogen (15N/14N, or δ15N) have been proposed as potential nutritional biomarkers to distinguish between meat, fish, and plant-based foods. Objective ...
    • Sleep duration and risk of fatal and nonfatal stroke 

      Leng, Y; Cappuccio, FP; Wainwright, NWJ; Surtees, PG; Luben, Robert; Brayne, Carol Elspeth; Khaw, Kay-Tee (Lippincott Williams & Wilkins/Wolters Kluwer Health, 2015-02-25)
      $\textbf{Objective:}$ To study the association between sleep duration and stroke incidence in a British population and to synthesize our findings with published results through a meta-analysis. $\textbf{Methods:}$ The ...
    • Smoking and high-risk mammographic parenchymal patterns: a case-control study 

      Sala, Evis; Warren, Ruth ML; McCann, Jenny; Duffy, Stephen; Luben, Robert; Day, Nicholas E (1999-11-16)
    • Sulfate, Nitrate and Blood Pressure - An EPIC Interaction between Sulfur and Nitrogen 

      Kuhnle, GG; Luben, Robert; Khaw, Kay-Tee; Feelisch, M
      Nitrate (NO3−)-rich foods such as green leafy vegetables are not only part of a healthy diet, but increasingly marketed for primary prevention of cardiovascular disease (CVD) and used as ergogenic aids by competitive ...
    • Television Viewing, Walking Speed and Grip Strength in a Prospective Cohort Study 

      Keevil, Victoria Louise; Wijndaele, Katrien Lieve; Luben, Robert; Sayer, Avan A; Wareham, Nicholas John; Khaw, Kay-Tee (2014-07-18)