Now showing items 58-72 of 72

• #### RAD51B in Familial Breast Cancer ﻿

(PLOS, 2016-05-05)
Common variation on 14q24.1, close to RAD51B, has been associated with breast cancer: rs999737 and rs2588809 with the risk of female breast cancer and rs1314913 with the risk of male breast cancer. The aim of this study ...
• #### Randomised trial of coconut oil, olive oil or butter on blood lipids and other cardiovascular risk factors in healthy men and women. ﻿

(BMJ Journals, 2018-03-06)
Abstract Introduction: High dietary saturated fat intake is associated with higher blood concentrations of LDL-cholesterol, an established risk factor for coronary heart disease. However, there is increasing interest ...
• #### Rare, protein-truncating variants in $\textit{ATM}$, $\textit{CHEK2}$ and $\textit{PALB2}$, but not $\textit{XRCC2}$, are associated with increased breast cancer risks ﻿

BACKGROUND: Breast cancer (BC) is the most common malignancy in women and has a major heritable component. The risks associated with most rare susceptibility variants are not well estimated. To better characterise the ...
• #### The relationship between dietary magnesium intake, stroke and its major risk factors, blood pressure and cholesterol, in the EPIC-Norfolk cohort ﻿

(Elsevier, 2015-05-31)
Background: Dietary magnesium could modify the major stroke risk factors, high blood pressure (BP) and cholesterol, but has been understudied in both sexes in a single population. This study aimed to investigate if dietary ...
• #### Retinal Nerve Fiber Layer Measures and Cognitive Function in the EPIC-Norfolk Cohort Study ﻿

(Association for Research in Vision and Ophthalmology, 2016-04)
$\textbf{Purpose.}$ We examined the relationship between retinal nerve fiber layer (RNFL) thickness and cognitive function in a population of older British adults. $\textbf{Methods.}$ Participants of the European Prospective ...
• #### Self-reported parkinsonian symptoms in the EPIC-Norfolk cohort ﻿

(2005-08-24)
Abstract Background Parkinsonian symptoms have been associated with increased morbidity and mortality. Several studies have reported on the prevalence of signs and symptoms. Symptoms questionnaires can identify potential ...
• #### Serum carbon and nitrogen stable isotopes as potential biomarkers of dietary intake and their relation with incident type 2 diabetes: the EPIC-Norfolk study ﻿

(American Society for Nutrition, 2014-07-02)
Background - Stable-isotope ratios of carbon (13C/12C, expressed as δ13C) and nitrogen (15N/14N, or δ15N) have been proposed as potential nutritional biomarkers to distinguish between meat, fish, and plant-based foods. Objective ...
• #### Sleep duration and risk of fatal and nonfatal stroke ﻿

(Lippincott Williams & Wilkins/Wolters Kluwer Health, 2015-02-25)
$\textbf{Objective:}$ To study the association between sleep duration and stroke incidence in a British population and to synthesize our findings with published results through a meta-analysis. $\textbf{Methods:}$ The ...
• #### Smoking and high-risk mammographic parenchymal patterns: a case-control study ﻿

(1999-11-16)
Statement of findings Current smoking was strongly and inversely associated with high-risk patterns, after adjustment for concomitant risk factors. Relative to never smokers, current smokers were significantly less likely ...
• #### Sulfate, Nitrate and Blood Pressure - An EPIC Interaction between Sulfur and Nitrogen ﻿

Nitrate (NO3−)-rich foods such as green leafy vegetables are not only part of a healthy diet, but increasingly marketed for primary prevention of cardiovascular disease (CVD) and used as ergogenic aids by competitive ...
• #### Television Viewing, Walking Speed and Grip Strength in a Prospective Cohort Study ﻿

(2014-07-18)
Purpose Television (TV) watching is the most prevalent sedentary leisure-time activity in the United Kingdom. We examined associations between TV viewing time, measured over 10 years, and two objective measures of ...
• #### Topical Beta-blockers and Cardiovascular Mortality: Systematic review and meta-analysis with data from the EPIC-Norfolk cohort study ﻿

(Taylor & Francis, 2016-08-23)
${\bf Purpose:}$ To determine if topical beta-blocker use is associated with increased cardiovascular mortality, particularly amongst people with self reported glaucoma. ${\bf Methods:}$ All participants who participated ...
• #### Weather, day length and physical activity in older adults: Cross-sectional results from the European Prospective Investigation into Cancer and Nutrition (EPIC) Norfolk Cohort ﻿

(Public Library of Science (PLoS), 2017-05-31)
$\textbf{Background}$ A wide range of environmental factors have been related to active ageing, but few studies have explored the impact of weather and day length on physical activity in older adults. We investigate the ...
• #### Weight change and 15 year mortality: results from the European Prospective Investigation into Cancer in Norfolk (EPIC-Norfolk) cohort study. ﻿

(Springer Nature, 2018-01)
Studies have reported a higher mortality risk associated with weight loss, particularly in middle-aged and older adults, although some of these studies did find that gaining weight was also associated with an increased ...
• #### ω-3 Polyunsaturated Fatty Acid Biomarkers and Coronary Heart Disease ﻿

(American Medical Association, 2016-06-27)
Importance The role of ω-3 polyunsaturated fatty acids for primary prevention of coronary heart disease (CHD) remains controversial. Most prior longitudinal studies evaluated self-reported consumption rather than ...