Now showing items 1-3 of 3

    • The impact of quantitative optimization of hybridization conditions on gene expression analysis 

      Sykacek, Peter; Kreil, David P; Meadows, Lisa A; Auburn, Richard P; Fischer, Bettina; Russell, Steven; Micklem, Gos (2011-03-14)
      Abstract Background With the growing availability of entire genome sequences, an increasing number of scientists can exploit oligonucleotide microarrays for genome-scale expression studies. While probe-design is a major ...
    • SimArray: a user-friendly and user-configurable microarray design tool 

      Auburn, Richard P; Russell, Roslin; Fischer, Bettina; Meadows, Lisa A; Sevillano, Matilla Santiago; Russell, Steven (2006-03-01)
      Abstract Background Microarrays were first developed to assess gene expression but are now also used to map protein-binding sites and to assess allelic variation between individuals. Regardless of the intended application, ...
    • Variable sexually dimorphic gene-expression in laboratory strains of Drosophila melanogaster 

      Baker, Dean Adam; Meadows, Lisa A; Wang, Jing; Dow, Julian AT; Russell, Steven (2007-12-10)
      Abstract Background Wild-type laboratory strains of model organisms are typically kept in isolation for many years, with the action of genetic drift and selection on mutational variation causing lineages to diverge with ...