Browsing by Author "Medina-Gomez, Gema"
Charalambous, Marika; Teixeira, Da Rocha Simao; Radford, Elizabeth Jane; Medina-Gomez, Gema; Curran, Scott; Pinnock, Scarlett B; Ferrón, Sacri RVidal-Puig, AntonioFerguson-Smith, Anne Carla et al. (2014-10-27)
Early Peroxisome proliferator-activated receptor gamma regulated genes involved in expansion of pancreatic beta cell mass Vivas, Yurena; Martinez-Garcia, Cristina; Izquierdo, Adriana; Garcia-Garcia, Francisco; Callejas, Sergio; Velasco, Ismael; Campbell, MarkRos, ManuelDopazo, AnaDopazo, JoaquinVidal-Puig, AntonioMedina-Gomez, Gema et al. (2011-12-30)Abstract Background The progression towards type 2 diabetes depends on the allostatic response of pancreatic beta cells to synthesise and secrete enough insulin to compensate for insulin resistance. The endocrine pancreas ...
Increased Dihydroceramide/ceramide ratio mediated by defective expression of degs1 impairs adipocyte differentiation and function Barbarroja, Nuria; Rodriguez-Cuenca, Sergio; Nygren, Heli; Camargo, Antonio; Pirraco, Ana; Relat, Joana; Cuadrado, IrenePellegrinelli, VanessaMedina-Gomez, GemaLopez-Pedrera, CharyTinahones, Francisco JSymons, J DavidSummers, Scott AOresic, MatejVidal-Puig, Sergio et al. (American Diabetes Association, 2014-10-28)Adipose tissue dysfunction is an important determinant of obesity-associated lipid induced metabolic complications. Ceramides are well known mediators of lipid induced insulin resistance in peripheral organs such as muscle. ...