Now showing items 1-8 of 8

    • Choline kinase alpha as an Androgen Receptor Chaperone and Prostate Cancer Therapeutic Target 

      Asim, Mohammad; Massie, Charles Edward; Orafidiya, Folake; Pértega-Gomes, Nelma; Warren, Anne Y; Esmaeili, Mohsen; Selth, Luke A et al. (2015)
    • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) 

      Klionsky, Daniel J; Abdelmohsen, Kotb; Abe, Akihisa; Abedin, Md Joynal; Abeliovich, Hagai; Arozena, Abraham Acevedo; Adachi, Hiroaki et al. (Taylor & Francis, 2016-01-21)
    • The Importance of DNA methylation in Prostate Cancer development 

      Massie, Charles Edward; Mills, Ian G; Lynch, Andrew Graeme (2016-04-24)
    • A new look towards BAC-based array CGH through a comprehensive comparison with oligo-based array CGH 

      Wicker, Nicolas; Carles, Annaick; Mills, Ian G; Wolf, Maija; Veerakumarasivam, Abhi; Edgren, Henrik; Boileau, Fabrice et al. (2007-03-29)
      Abstract Background Currently, two main technologies are used for screening of DNA copy number; the BAC (Bacterial Artificial Chromosome) and the recently developed oligonucleotide-based CGH (Chromosomal Comparative Genomic ...
    • Nuclear ARRB1 induces pseudohypoxia and cellular metabolism reprogramming in prostate cancer. 

      Zecchini, Vincent; Madhu, Madhu; Russell, Roslin; Pértega-Gomes, Nelma; Warren, Anne; Gaude, Edoardo; Borlido, Joana et al. (2014-06)
    • Polygenic hazard score to guide screening for aggressive prostate cancer: development and validation in large scale cohorts. 

      Seibert, Tyler M; Fan, Chun Chieh; Wang, Yunpeng; Zuber, Verena; Karunamuni, Roshan; Parsons, J Kellogg; Eeles, Rosalind A et al.
      Objectives: Prostate-specific-antigen (PSA) screening resulted in reduced prostate cancer (PCa) mortality in a large clinical trial, but due to many false positives and overdiagnosis of indolent disease, many guidelines ...
    • Pro-neural transcription factors as cancer markers 

      Vias, Maria; Massie, Charles Edward; East, Philip; Scott, Helen; Warren, Anne; Zhou, Zongxiang; Nikitin, Alexander Yu et al. (2008-05-19)
      Abstract Background The aberrant transcription in cancer of genes normally associated with embryonic tissue differentiation at various organ sites may be a hallmark of tumour progression. For example, neuroendocrine ...
    • Synthetic lethality between androgen receptor signalling and the PARP pathway in prostate cancer. 

      Asim, Mohammad; Tarish, Firas; Zecchini, Heather I; Sanjiv, Kumar; Gelali, Eleni; Massie, Charles Edward; Baridi, Ajoeb et al. (Nature Publishing Group, 2017-08-29)
      Emerging data demonstrate homologous recombination (HR) defects in castration resistant prostate cancers, rendering these tumours sensitive to PARP inhibition. Here, we demonstrate a direct requirement for the androgen ...