Browsing by Author "Ng, Charlotte"
Swanton, Charles; Nicke, Barbara; Schuett, Marion; Eklund, Aron C.; Ng, Charlotte; Li, Qiyuan; Hardcastle, ThomasLee, AlvinRoy, RajatEast, PhilipKschischo, MaikEndesfelder, DavidWylie, PaulKim, Se NyunChen, Jie-GuangHowell, MichaelRied, ThomasHabermann, Jens K.Auer, GertBrenton, James D.Szallasi, ZoltanDownward, Julian et al. (2009-04-24)Microtubule-stabilizing (MTS) agents, such as taxanes, are important chemotherapeutics with a poorly understood mechanism of action. We identified a set of genes repressed in multiple cell lines in response to MTS agents ...
Spatial and temporal heterogeneity in high-grade serous ovarian cancer: a phylogenetic reconstruction Schwarz, Roland F; Ng, Charlotte; Cooke, Susanna L; Newmann, Scott; Temple, Jillian; Piskorz, Anna; Gale, DavinaSayal, KarenMurtaza, MuhammedBaldwin, Peter JRosenfeld, NitzanEarl, Helena MargaretSala, EvisJimenez-Linan, MercedesParkinson, Christine AMarkowetz, FlorianBrenton, James Derek et al. (PLOS, 2015-02-24)Background The major clinical challenge in the treatment of high-grade serous ovarian cancer (HGSOC) is the development of progressive resistance to platinum-based chemotherapy. The objective of this study was to determine ...
Structural analysis of the genome of breast cancer cell line ZR-75-30 identifies twelve expressed fusion genes Schulte, Ina; Batty, Elizabeth M; Pole, Jessica CM; Blood, Katherine A; Mo, Steven; Cooke, Susanna L; Ng, CharlotteHowe, Kevin LChin, Suet FeungBrenton, James DerekCaldas, Carlos ManuelHowarth, KarenEdwards, Paul Anthony et al. (2012-12-22)