Browsing by Author "Nicke, Barbara"

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Chromosomal instability determines taxane sensitivity - supplementary materials

Swanton, Charles; Nicke, Barbara; Schuett, Marion; Eklund, Aron C.; Ng, Charlotte; Li, Qiyuan; Hardcastle, ThomasLee, AlvinRoy, RajatEast, PhilipKschischo, MaikEndesfelder, DavidWylie, PaulKim, Se NyunChen, Jie-GuangHowell, MichaelRied, ThomasHabermann, Jens K.Auer, GertBrenton, James D.Szallasi, ZoltanDownward, Julian et al. (2009-04-24)

Microtubule-stabilizing (MTS) agents, such as taxanes, are important chemotherapeutics with a poorly understood mechanism of action. We identified a set of genes repressed in multiple cell lines in response to MTS agents ...