Now showing items 8-9 of 9

    • Investigating the utility of combining Phi29 whole genome amplification and highly multiplexed single nucleotide polymorphism BeadArrayTM genotyping 

      Pask, Rebecca; Rance, Helen E; Barratt, Bryan J; Nutland, Sarah; Smyth, Deborah J; Sebastian, Meera; Twells, Rebecca CJ et al. (2004-07-27)
      Background: Sustainable DNA resources and reliable high-throughput genotyping methods are required for large-scale, long-term genetic association studies. In the genetic dissection of common disease it is now recognised ...
    • Sequencing and association analysis of the type 1 diabetes - linked region on chromosome 10p12-q11. 

      Nejentsev, Sergey; Smink, Luc J; Smyth, Deborah J; Bailey, Rebecca; Lowe, Christopher Eric; Payne, Felicity; Masters, Jennifer et al. (2007-05-17)
      Background: In an effort to locate susceptibility genes for type I diabetes (TID) several genome-wide linkage scans have been undertaken. A chromosomal region designated IDDM10 retained genome-wide significance in a combined ...