Now showing items 1-2 of 2

    • Evidence for SMAD3 as a modifier of breast cancer risk in BRCA2 mutation carriers 

      Walker, Logan C.; Fredericksen, Zachary S.; Wang, Xianshu; Tarrell, Robert; Pankratz, Vernon Shane; Lindor, Noralane M.; Beesley, Jonathan et al. (2010-11-29)
      Abstract Introduction Current attempts to identify genetic modifiers of BRCA1 and BRCA2 associated risk have focused on a candidate gene approach, based on knowledge of gene functions, or the development of large genome-wide ...
    • Genetic variation in stromal proteins decorin and lumican with breast cancer: investigations in two case-control studies 

      Kelemen, Linda E.; Couch, Fergus J.; Ahmed, Shahana; Dunning, Alison M.; Pharoah, Paul D. P.; Easton, Douglas F.; Fredericksen, Zachary S. et al. (2008-11-26)
      Abstract Introduction The stroma is the supportive framework of biologic tissue in the breast, consisting of various proteins such as the proteoglycans, decorin and lumican. Altered expression of decorin and lumican is ...