Now showing items 1-4 of 4

    • Characterization of intrinsic properties of promoters 

      Rudge, Timothy James; Brown, James Robert; Federici, Fernan; Dalchau, Neil; Phillips, Andrew; Ajioka, James Warren; Haseloff, James Phillip (ACS, 2015-10-05)
      Accurate characterization of promoter behavior is essential for the rational design of functional synthetic transcription networks such as logic gates and oscillators. However, transcription rates observed from promoters ...
    • Computational modeling of the EGFR network elucidates control mechanisms regulating signal dynamics 

      Wang, Dennis YQ; Cardelli, Luca; Phillips, Andrew; Piterman, Nir; Fisher, Jasmin (2009-12-22)
      Abstract Background The epidermal growth factor receptor (EGFR) signaling pathway plays a key role in regulation of cellular growth and development. While highly studied, it is still not fully understood how the signal is ...
    • Orthogonal intercellular signaling for programmed spatial behavior. 

      Grant, Paul K; Dalchau, Neil; Brown, James R; Federici, Fernan; Rudge, Timothy J; Yordanov, Boyan; Patange, Om et al. (European Molecular Biology Organization, 2016-01-25)
      Bidirectional intercellular signaling is an essential feature of multicellular organisms, and the engineering of complex biological systems will require multiple pathways for intercellular signaling with minimal crosstalk. ...
    • Studies Towards the Total Synthesis of Patellazole B 

      Phillips, Andrew (2017-11-08)
      The patellazoles are a family of marine polyketide natural products first isolated from Lissoclinum patella in 1988 by both the Moore and Ireland groups. They exhibit significant cytotoxicity against the HCT 116 human colon ...