Now showing items 1-2 of 2

    • Both common variations and rare non-synonymous substitutions and small insertion/deletions in CLU are associated with increased Alzheimer risk 

      Bettens, Karolien; Brouwers, Nathalie; Engelborghs, Sebastiaan; Lambert, Jean-Charles; Rogaeva, Ekaterina; Vandenberghe, Rik; Le Bastard, Nathalie et al. (2012-01-16)
      Abstract Background We have followed-up on the recent genome-wide association (GWA) of the clusterin gene (CLU) with increased risk for Alzheimer disease (AD), by performing an unbiased resequencing of all CLU coding exons ...
    • Role of p73 in Alzheimer disease: lack of association in mouse models or in human cohorts 

      Vardarajan, Badri; Vergote, David; Tissir, Fadel; Logue, Mark; Yang, Jing; Daude, Nathalie; Ando, Kunie et al. (2013-02-15)
      Abstract Background P73 belongs to the p53 family of cell survival regulators with the corresponding locus Trp73 producing the N-terminally distinct isoforms, TAp73 and DeltaNp73. Recently, two studies have implicated the ...