Now showing items 2-5 of 5

    • Conserved genomic organisation of Group B Sox genes in insects. 

      McKimmie, Carol; Woerfel, Gertrud; Russell, Steven R (2005-05-19)
      Abstract Background Sox domain containing genes are important metazoan transcriptional regulators implicated in a wide rage of developmental processes. The vertebrate B subgroup contains the Sox1, Sox2 and Sox3 genes that ...
    • FlyMine: an integrated database for Drosophila and Anopheles genomics 

      Lyne, Rachel; Smith, Richard; Rutherford, Kim; Wakeling, Matthew; Varley, Andrew; Guillier, Francois; Janssens, Hilde et al. (2007-07-05)
      Abstract FlyMine is a data warehouse that addresses one of the important challenges of modern biology: how to integrate and make use of the diversity and volume of current biological data. Its main focus is genomic and ...
    • Genomic analysis of heat-shock factor targets in Drosophila 

      Birch-Machin, Ian; Gao, Shan; Huen, David S; McGirr, Richard; White, Robert A H; Russell, Steven R (2005-06-10)
      Abstract We have used a chromatin immunoprecipitation-microarray (ChIP-array) approach to investigate the in vivo targets of heat-shock factor (Hsf) in Drosophila embryos. We show that this method identifies Hsf target ...
    • On the use of resampling tests for evaluating statistical significance of binding-site co-occurrence 

      Huen, David S; Russell, Steven R (2010-06-30)
      Abstract Background In eukaryotes, most DNA-binding proteins exert their action as members of large effector complexes. The presence of these complexes are revealed in high-throughput genome-wide assays by the co-occurrence ...