Now showing items 3-4 of 4

    • Common genetic variants highlight the role of insulin resistance and body fat distribution in type 2 diabetes, independently of obesity 

      Scott, Robert A.; Fall, Tove; Pasko, Dorota; Barker, Adam; Sharp, Stephen J.; Arriola, Larraitz; Balkau, Beverley et al. (American Diabetes Association, 2014-06-19)
      We aimed to validate genetic variants as instruments for insulin resistance and secretion, to characterise their association with intermediate phenotypes, and to investigate their role in T2D risk among normal-weight, ...
    • The INSIG2 rs7566605 polymorphism is not associated with body mass index and breast cancer risk 

      Campa, Daniele; Husing, Anika; McKay, James D.; Sinilnikova, Olga M.; Vogel, Ulla; Tjonneland, Anne; Overvad, Kim et al. (2010-10-18)
      Abstract Background The single nucleotide polymorphism rs7566605, located in the promoter of the INSIG2 gene, has been the subject of a strong scientific effort aimed to elucidate its possible association with body mass ...