Now showing items 1-3 of 3

    • Dictyostelium transcriptional responses to Pseudomonas aeruginosa: common and specific effects from PAO1 and PA14 strains 

      Carilla-Latorre, Sergio; Calvo-Garrido, Javier; Bloomfield, Gareth; Skelton, Jason; Kay, Robert R.; Ivens, Alasdair; Martinez, Jose L. et al. (2008-06-30)
      Abstract Background Pseudomonas aeruginosa is one of the most relevant human opportunistic bacterial pathogens. Two strains (PAO1 and PA14) have been mainly used as models for studying virulence of P. aeruginosa. The strain ...
    • Targets downstream of Cdk8 in Dictyostelium development 

      Greene, David M.; Bloomfield, Gareth; Skelton, Jason; Ivens, Alasdair; Pears, Catherine J. (2011-01-21)
      Abstract Background Cdk8 is a component of the mediator complex which facilitates transcription by RNA polymerase II and has been shown to play an important role in development of Dictyostelium discoideum. This eukaryote ...
    • Widespread duplications in the genomes of laboratory stocks of Dictyostelium discoideum 

      Bloomfield, Gareth; Tanaka, Yoshimasa; Skelton, Jason; Ivens, Alasdair; Kay, Robert R. (2008-04-22)
      Abstract Background Duplications of stretches of the genome are an important source of individual genetic variation, but their unrecognized presence in laboratory organisms would be a confounding variable for genetic ...