Browsing by Author "Stoppa-Lyonnet, Dominique"
Now showing items 3-12 of 12
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Common breast cancer susceptibility alleles are associated with tumor subtypes in BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2.
Mulligan, Anna Marie; Couch, Fergus J.; Barrowdale, Daniel; Domchek, Susan M.; Eccles, Diana; Nevanlinna, Heli; Ramus, Susan J.Robson, MarkSherman, MarkSpurdle, Amanda B.Wappenschmidt, BarbaraAntoniou, Antonis C.Family Registry, Breast CancerEmbraceCollaborators, GEMO StudyHebonNetwork, Ontario Cancer GeneticsSwe-brcaCimbaOsorio, AnaMunoz-Repeto, IvanCoupier, IsabelleDuran, MercedesGodino, JavierPertesi, MaroulioBenitez, JavierPeterlongo, PaoloManoukian, SiranoushPeissel, BernardZaffaroni, DanielaCattaneo, ElisaBonanni, BernardoLebrun, MarineViel, AlessandraPasini, BarbaraPapi, LauraOttini, LauraSavarese, AntonellaBernard, LorisRadice, PaoloHamann, UteVerheus, MartijnMeijers-Heijboer, Hanne E. J.Kientz, CarolineWijnen, JuulGomez Garcia, Encarna B.Nelen, Marcel R.Kets, C. MarleenSeynaeve, CarolineTilanus-Linthorst, Madeleine M. A.van der Luijt, Rob B.van Os, Theo A.Rookus, MattiFrost, DebraLongy, MichelJones, J. LouiseEvans, D. GarethLalloo, FionaEeles, RosIzatt, LouiseAdlard, JulianDavidson, RosemarieCook, JackieDonaldson, AlanDorkins, HuwSevenet, NicolasGregory, HelenEason, JacquelineHoughton, CatherineBarwell, JulianSide, Lucy E.McCann, EmmaMurray, AlexPeock, SusanGodwin, AndrewSchmutzler, Rita K.Stoppa-Lyonnet, DominiqueRhiem, KerstinEngel, ChristophMeindl, AlfonsRuehl, InaArnold, NorbertNiederacher, DieterSutter, ChristianDeissler, HelmutGadzicki, DorotheaKast, KarinIsaacs, ClaudinePreisler-Adams, SabineVaron-Mateeva, RaymondaSchoenbuchner, InesFiebig, BrittaHeinritz, WolframSchafer, DieterGevensleben, HeidrunCaux-Moncoutier, VirginieFassy-Colcombet, MarionCornelis, FrancoisCaldes, TrinidadMazoyer, SylvieLeone, MelanieBoutry-Kryza, NadiaHardouin, AgnesBerthet, PascalineMuller, DanieleFricker, Jean-PierreMortemousque, IsabellePujol, Pascalde al Hoya, MiguelHeikkinen, TuomasLee, AndrewAittomaki, KristiinaBlanco, IgnacioLazaro, ConxiBarkardottir, Rosa B.Soucy, PennyDumont, MartineSimard, JacquesMontagna, MarcoTognazzo, SilviaD'Andrea, EmmaMcGuffog, LesleyFox, StephenYan, MaxRebbeck, Timothy R.Olopade, Olufunmilayo I.Weitzel, Jeffrey N.Lynch, Henry T.Ganz, Patricia A.Tomlinson, Gail E.Wang, XianshuFredericksen, ZacharyHealey, SuePankratz, Vernon S.Lindor, Noralane M.Szabo, CsilaOffit, KennethSakr, RitaGaudet, MiaBhatia, JasmineKauff, NoahSinger, Christian F.Tea, Muy-KhengSinilnikova, Olga M.Gschwantler-Kaulich, DaphneFink-Retter, AnnelieseMai, Phuong L.Greene, Mark H.Imyanitov, EvgenyO'Malley, Frances P.Ozcelik, HilmiGlendon, GordonToland, Amanda E.Gerdes, Anne-MarieJanavicius, RamunasThomassen, MadsKruse, Torben A.Birk Jensen, UffeSkytte, Anne-BineCaligo, Maria A.Soller, MariaHenriksson, Karinvon Wachenfeldt, AnnaArver, BritaStenmark-Askmalm, MarieHansen, Thomas V. O.Karlsson, PerDing, Yuan ChunNeuhausen, Susan L.Beattie, MaryPharoah, Paul D. P.Moysich, Kirsten B.Nathanson, Katherine L.Karlan, Beth Y.Gross, JennyJohn, Esther M.Nielsen, Finn C.Daly, Mary B.Buys, Saundra M.Southey, Melissa C.Hopper, John L.Terry, Mary BethChung, WendyMiron, Alexander F.Goldgar, DavidChenevix-Trench, GeorgiaEaston, Douglas F.Ejlertsen, BentAndrulis, Irene L. et al. (2011-11-02)Abstract Introduction Previous studies have demonstrated that common breast cancer susceptibility alleles are differentially associated with breast cancer risk for BRCA1 and/or BRCA2 mutation carriers. It is currently ... -
Effects of BRCA2 cis-regulation in normal breast and cancer risk amongst BRCA2 mutation carriers
Maia, Ana-Teresa; Antoniou, Antonis C.; O'Reilly, Martin; Samarajiwa, Shamith; Dunning, Mark; Kartsonaki, Christiana; Chin, Suet-FeungCurtis, Christina N.McGuffog, LesleyDomchek, Susan M.Embrace, EmbraceEaston, Douglas F.Peock, SusanFrost, DebraEvans, D. GarethEeles, RosIzatt, LouiseAdlard, JulianEccles, DianaGemo, GemoSinilnikova, Olga M.Mazoyer, SylvieStoppa-Lyonnet, DominiqueGauthier-Villars, MarionFaivre, LaurenceVenat-Bouvet, LaurenceDelnatte, CapucineNevanlinna, HeliCouch, Fergus J.Godwin, Andrew K.Caligo, Maria AdelaideSwe-brca, Swe-brcaBarkardottir, Rosa B.kConFab, kConFabChen, XiaoqingBeesley, JonathanHealey, SueCaldas, CarlosChenevix-Trench, GeorgiaPonder, Bruce A. J. et al. (2012-04-18)Abstract Introduction Cis-acting regulatory single nucleotide polymorphisms (SNPs) at specific loci may modulate penetrance of germline mutations at the same loci by introducing different levels of expression of the wild-type ... -
Evidence for SMAD3 as a modifier of breast cancer risk in BRCA2 mutation carriers
Walker, Logan C.; Fredericksen, Zachary S.; Wang, Xianshu; Tarrell, Robert; Pankratz, Vernon Shane; Lindor, Noralane M.; Beesley, JonathanHealey, SueChen, Xiaoqing(kConFab), Kathleen Cuningham Foundation Consortium for ResearchStoppa-Lyonnet, DominiqueTirapo, CaroleGiraud, SophieMazoyer, SylvieMuller, DanieleFricker, Jean-PierreDelnatte, Capucine(gemo), Groupe Genetique et CancerSchmutzler, Rita K.Wappenschmidt, BarbaraEngel, ChristophSchonbuchner, InesDeissler, HelmutMeindl, AlfonsHogervorst, Frans B.Verheus, MartijnHooning, Maartje J.van den Ouweland, Ans M. W.Nelen, Marcel R.Ausems, Margreet G. E. M.Aalfs, Cora M.van Asperen, Christi J.Devilee, PeterGerrits, Monique M.Waisfisz, Quinten(hebon), Hereditary Breast and Ovarian Cancer Research Group NetherlandsSzabo, Csilla I.ModSQuaD, TheEaston, Douglas F.Peock, SusanCook, MargaretOliver, Clare T.Frost, DebraHarrington, PatriciaEvans, D. GarethLalloo, FionaEeles, RosalindIzatt, LouiseChu, CarolDavidson, RosemarieEccles, DianaOng, Kai-RenCook, JackieEmbrace, TheRebbeck, Timothy R.Nathanson, Katherine L.Domchek, Susan M.Singer, Christian F.Gschwantler-Kaulich, DaphneDressler, Anne-CatharinaPfeiler, GeorgGodwin, Andrew K.Heikkinen, TuomasNevanlinna, HeliAgnarsson, Bjarni A.Caligo, Maria AdelaideOlsson, HakanKristoffersson, UlfLiljegren, AnnelieArver, BritaKarlsson, PerMelin, Beatrice(swe-brca), Swedish Breast Cancer StudySinilnikova, Olga M.McGuffog, LesleyAntoniou, Antonis C.Chenevix-Trench, GeorgiaSpurdle, Amanda B.Couch, Fergus J. et al. (2010-11-29)Abstract Introduction Current attempts to identify genetic modifiers of BRCA1 and BRCA2 associated risk have focused on a candidate gene approach, based on knowledge of gene functions, or the development of large genome-wide ... -
Exploring the link between MORF4L1 and risk of breast cancer
Martrat, Griselda; Maxwell, Christopher A.; Tominaga, Emiko; Porta, Montserrat; Bonifaci, Nuria; Gomez-Baldo, Laia; Bogliolo, MassimoLazaro, ConxiBlanco, IgnacioBrunet, JoanAguilar, HelenaUhrhammer, NancyTorres, DianaCaligo, Maria AdelaideGodwin, Andrew K.Fernandez-Rodriguez, JuanaImyanitov, Evgeny N.Janavicius, Ramunas(gemo), Groupe Genetique et CancerSinilnikova, Olga M.Stoppa-Lyonnet, DominiqueDavidson, RosemarieMazoyer, SylviePeyrat, Jean-PhilippeVerny-Pierre, CaroleCastera, Laurentde Pauw, AntoineBignon, Yves-JeanVennin, PhilippeFert Ferrer, SandraCollonge-Rame, Marie-AgnesMortemousque, IsabelleRamirez, Maria J.McGuffog, LesleyChenevix-Trench, GeorgiaPereira-Smith, Olivia M.Chu, CarolAntoniou, Antonis C.Renwick, AnthonyCeron, JulianTominaga, KaoruSurralles, JordiPujana, Miguel AngelCastella, MariaRahman, NazneenKuhl, JuliaNeveling, KorneliaSchindler, DetlevHernandez, Gonzalo(embrace), Epidemiological Study of Familial Breast CancersEaston, Douglas F.Peock, SusanCook, MargaretOliver, Clare T.Frost, DebraBlok, Marinus J.Platte, RadkaOng, Kai-RenEvans, D. GarethLalloo, FionaEeles, RosalindIzatt, LouiseCook, JackieDouglas, FionaHodgson, Shirley V.Brewer, CaroleBernard, LorisMorrison, Patrick J.Porteous, MaryPeterlongo, Paolovan Os, Theo A.Manoukian, SiranoushPeissel, BernardZaffaroni, DanielaRoversi, GaiaBarile, MonicaViel, AlessandraRadice, PaoloPasini, BarbaraOttini, LauraPutignano, Anna LauraSavarese, AntonellaHealey, SueSpurdle, Amanda B.Chen, XiaoqingBeesley, Jonathan(kConFab), Kathleen Cuningham Foundation Consortium for ResearchRookus, Matti A.Verhoef, SennoOsorio, AnaTilanus-Linthorst, Madeleine A.Meijers-Heijboer, Hanne E. J.Vreeswijk, Maaike P.Asperen, Christi J.Bodmer, DanielleAusems, Margreet G. E. M.Hogervorst, Frans B.(hebon), Hereditary Breast and Ovarian Cancer Research Group NetherlandsGoldgar, David E.Buys, SaundraLaitman, YaelJohn, Esther M.Miron, AlexanderSouthey, Melissa C.Caldes, TrinidadDaly, Mary B.(bcfr), Breast Cancer Family Registry(swe-brca), Swedish Breast Cancer StudyHarbst, KatjaBorg, AkeRantala, JohannaMilgrom, RoniBarbany-Bustinza, GiselaEhrencrona, HansStenmark-Askmalm, MarieKaufman, BellaFriedman, EitanDomchek, Susan M.Nathanson, Katherine L.Rebbeck, Timothy R.Johannsson, Oskar ThorCouch, Fergus J.Wang, XianshuSeal, SheilaFredericksen, Zachary S.Benitez, JavierCuadras, DanielMoreno, VictorPientka, Friederike K.Depping, ReinhardBueren, JuanHeikkinen, TuomasNevanlinna, HeliHamann, Ute et al. (2011-04-05)Abstract Introduction Proteins encoded by Fanconi anemia (FA) and/or breast cancer (BrCa) susceptibility genes cooperate in a common DNA damage repair signaling pathway. To gain deeper insight into this pathway and its ... -
Fine-Scale Mapping at 9p22.2 Identifies Candidate Causal Variants That Modify Ovarian Cancer Risk in $\small \textit{BRCA1}$ and $\small \textit{BRCA2}$ Mutation Carriers
Vigorito, Elena; Kuchenbaecker, Karoline B.; Beesley, Jonathan; Adlard, Julian; Agnarsson, Bjarni A.; Andrulis, Irene L.; Arun, Banu K.Barjhoux, LaureBelotti, MurielBenitez, JavierBerger, AndreasBojesen, AndersBonanni, BernardoBrewer, CaroleCaldes, TrinidadCaligo, Maria A.Campbell, IanChan, Salina B.Claes, Kathleen B. M.Cohn, David E.Cook, JackieDaly, Mary B.Damiola, FrancescaDavidson, RosemariePauw, Antoine deDelnatte, CapucineDiez, OrlandDomchek, Susan M.Dumont, MartineDurda, KatarzynaDworniczak, BerndEaston, Douglas F.Eccles, DianaEdwinsdotter Ardnor, ChristinaEeles, RosEjlertsen, BentEllis, SteveEvans, D. GarethFeliubadalo, LidiaFostira, FlorentiaFoulkes, William D.Friedman, EitanFrost, DebraGaddam, PragnaGanz, Patricia A.Garber, JudyGarcia-Barberan, VanesaGauthier-Villars, MarionGehrig, AndreaGerdes, Anne-MarieGiraud, SophieGodwin, Andrew K.Goldgar, David E.Hake, Christopher R.Hansen, Thomas V. O.Healey, SueHodgson, ShirleyHogervorst, Frans B. L.Houdayer, ClaudeHulick, Peter J.Imyanitov, Evgeny N.Isaacs, ClaudineIzatt, LouiseIzquierdo, AngelJacobs, LaurenJakubowska, AnnaJanavicius, RamunasJaworska-Bieniek, KatarzynaJensen, Uffe BirkJohn, Esther M.Vijai, JosephKarlan, Beth Y.Kast, KarinInvestigators, KConFabKhan, SofiaKwong, AvaLaitman, YaelLester, JennyLesueur, FabienneLiljegren, AnnelieLubinski, JanMai, Phuong L.Manoukian, SiranoushMazoyer, SylvieMeindl, AlfonsMensenkamp, Arjen R.Montagna, MarcoNathanson, Katherine L.Neuhausen, Susan L.Nevanlinna, HeliNiederacher, DieterOlah, EdithOlopade, Olufunmilayo I.Ong, Kai-renOsorio, AnaPark, Sue KyungPaulsson-Karlsson, YlvaPedersen, Inge SokildePeissel, BernardPeterlongo, PaoloPfeiler, GeorgPhelan, Catherine M.Piedmonte, MarionPoppe, BrucePujana, Miquel AngelRadice, PaoloRennert, GadRodriguez, Gustavo C.Rookus, Matti A.Ross, Eric A.Schmutzler, Rita KatharinaSimard, JacquesSinger, Christian F.Slavin, Thomas P.Soucy, PennySouthey, MelissaSteinemann, DorisStoppa-Lyonnet, DominiqueSukiennicki, GrzegorzSutter, ChristianSzabo, Csilla I.Tea, Muy-KhengTeixeira, Manuel R.Teo, Soo-HwangTerry, Mary BethThomassen, MadsTibiletti, Maria GraziaTihomirova, LaimaTognazzo, Silviavan Rensburg, Elizabeth J.Varesco, LilianaVaron-Mateeva, RaymondaVratimos, AthanassiosWeitzel, Jeffrey N.McGuffog, LesleyKirk, JudyToland, Amanda EwartHamann, UteLindor, NoralaneRamus, Susan J.Greene, Mark H.Couch, Fergus J.Offit, KennethPharoah, Paul D. P.Chenevix-Trench, GeorgiaAntoniou, Antonis C. et al. (Public Library of Science, 2016-07-27)Population-based genome wide association studies have identified a locus at 9p22.2 associated with ovarian cancer risk, which also modifies ovarian cancer risk in $\small \textit{BRCA1}$ and $\small \textit{BRCA2}$ mutation ... -
Functional Mechanisms Underlying Pleiotropic Risk Alleles at the 19p13.1 Breast-Ovarian Cancer Susceptibility Locus
Lawrenson, Kate; Kar, Siddhartha; McCue, Karen; Kuchenbaeker, Karoline; Michailidou, Kyriaki; Tyrer, Jonathan; Beesley, JonathanRamus, Susan J.Li, QiyuanDelgado, Melissa K.Lee, Janet M.Aittomäki, KristiinaAndrulis, Irene L.Anton-Culver, HodaArndt, VolkerArun, Banu K.Arver, BritaBandera, Elisa V.Barile, MonicaBarkardottir, Rosa B.Barrowdale, DanielBeckmann, Matthias W.Benitez, JavierBerchuck, AndrewBisogna, MariaBjorge, LineBlomqvist, CarlBlot, WilliamBogdanova, NataliaBojesen, AndersBojesen, Stig E.Bolla, Manjeet K.Bonanni, BernardoBorresen-Dale, Anne-LiseBrauch, HiltrudBrennan, PaulBrenner, HermannBruinsma, FionaBrunet, JoanBuhari, Shaik AhmadBurwinkel, BarbaraButzow, RalfBuys, Saundra S.Cai, QiuyinCaldes, TrinidadCampbell, IanCanniotto, RikkiChang-Claude, JennyChiquette, JocelyneChoi, Ji-YeobClaes, Kathleen B. M.GEMO Study CollaboratorsCook, Linda S.Cox, AngelaCramer, Daniel W.Cross, Simon S.Cybulski, CezaryCzene, KamilaDaly, Mary B.Damiola, FrancescaDansonka-Mieszkowska, AgnieszkaDarabi, HatefDennis, JoeDevilee, PeterDiez, OrlandDoherty, Jennifer A.Domchek, Susan M.Dorfling, Cecilia M.Dörk, ThiloDumont, MartineEhrencrona, HansEjlertsen, BentEllis, SteveEMBRACEEngel, ChristophLee, EunjungEvans, D. GarethFasching, Peter A.Feliubadalo, LidiaFigueroa, JonineFlesch-Janys, DieterFletcher, OliviaFlyger, HenrikForetova, LenkaFostira, FlorentiaFoulkes, William D.Fridley, Brooke L.Friedman, EitanFrost, DebraGambino, GaetanaGanz, Patricia A.Garber, JudyGarcía-Closas, MontserratGentry-Maharaj, AleksandraGhoussaini, MayaGiles, Graham G.Glasspool, RosalindGodwin, Andrew K.Goldberg, Mark S.Goldgar, David E.González-Neira, AnnaGoode, Ellen L.Goodman, Marc T.Greene, Mark H.Gronwald, JacekGuénel, PascalHaiman, Christopher A.Hall, PerHallberg, EmilyHamann, UteHansen, Thomas V. O.Harrington, Patricia A.Hartman, MikaelHassan, NorhashimahHealey, SueHEBONHeitz, FlorianHerzog, JosefHøgdall, EstridHøgdall, Claus K.Hogervorst, Frans B. L.Hollestelle, AntoinetteHopper, John L.Hulick, Peter J.Huzarski, TomaszImyanitov, Evgeny N.KConFab InvestigatorsAustralian Ovarian Cancer Study GroupIsaacs, ClaudineIto, HidemiJakubowska, AnnaJanavicius, RamunasJensen, AllanJohn, Esther M.Johnson, NicholaKabisch, MariaKang, DaeheeKapuscinski, MiroslavKarlan, Beth Y.Khan, SofiaKiemeney, Lambertus A.Kjaer, Susanne KrugerKnight, Julia A.Konstantopoulou, IreneKosma, Veli-MattiKristensen, VesselaKupryjanczyk, JolantaKwong, AvaHoya, Miguel de laLaitman, YaelLambrechts, DietherLe, NhuLeeneer, Kim DeLester, JennyLevine, Douglas A.Li, JingmeiLindblom, AnnikaLong, JirongLophatananon, ArtitayaLoud, Jennifer T.Lu, KarenLubinski, JanMannermaa, ArtoManoukian, SiranoushMarchand, Loic LeMargolin, SaraMarme, FrederikMassuger, Leon F. A. G.Matsuo, KeitaroMazoyer, SylvieMcGuffog, LesleyMcLean, CatrionaMcNeish, IainMeindl, AlfonsMenon, UshaMensenkamp, Arjen R.Milne, Roger L.Montagna, MarcoMoysich, Kirsten B.Muir, KennethMulligan, Anna MarieNathanson, Katherine L.Ness, Roberta B.Neuhausen, Susan L.Nevanlinna, HeliNord, SiljeNussbaum, Robert L.Odunsi, KunleOffit, KennethOlah, EdithOlopade, Olufunmilayo I.Olson, Janet E.Olswold, CurtisO’Malley, DavidOrlow, IreneOrr, NickOsorio, AnaPark, Sue KyungPearce, Celeste L.Pejovic, TanjaPeterlongo, PaoloPfeiler, GeorgPhelan, Catherine M.Poole, Elizabeth M.Pylkäs, KatriRadice, PaoloRantala, JohannaRashid, Muhammad UsmanRennert, GadRhenius, ValerieRhiem, KerstinRisch, Harvey A.Rodriguez, GusRossing, Mary AnneRudolph, AnjaSalvesen, Helga B.Sangrajrang, SuleepornSawyer, Elinor J.Schildkraut, Joellen M.Schmidt, Marjanka K.Schmutzler, Rita K.Sellers, Thomas A.Seynaeve, CarolineShah, MitulShen, Chen-YangShu, Xiao-OuSieh, WeivaSinger, Christian F.Sinilnikova, Olga M.Slager, SusanSong, HonglinSoucy, PennySouthey, Melissa C.Stenmark-Askmalm, MarieStoppa-Lyonnet, DominiqueSutter, ChristianSwerdlow, AnthonyTchatchou, SandrineTeixeira, Manuel R.Teo, Soo H.Terry, Kathryn L.Terry, Mary BethThomassen, MadsTibiletti, Maria GraziaTihomirova, LaimaTognazzo, SilviaToland, Amanda EwartTomlinson, IanTorres, DianaTruong, ThérèseTseng, Chiu-chenTung, NadineTworoger, Shelley S.Vachon, CelineOuweland, Ans M. W. van denDoorn, Helena C. vanRensburg, Elizabeth J. vanVeer, Laura J. Van'tVanderstichele, AdriaanVergote, IgnaceVijai, JosephWang, QinWang-Gohrke, ShanWeitzel, Jeffrey N.Wentzensen, NicolasWhittemore, Alice S.Wildiers, HansWinqvist, RobertWu, Anna H.Yannoukakos, DrakoulisYoon, Sook-YeeYu, Jyh-CherngZheng, WeiZheng, YingKhanna, Kum KumSimard, JacquesMonteiro, Alvaro N.French, Juliet D.Couch, Fergus J.Freedman, Matthew L.Easton, Douglas F.Dunning, Alison M.Pharoah, Paul D.Edwards, Stacey L.Chenevix-Trench, GeorgiaAntoniou, Antonis C.Gayther, Simon A. et al. (Nature Publishing Group, 2016)A locus at 19p13 is associated with breast cancer (BC) and ovarian cancer (OC) risk. We analyzed 438 SNPs in this region in 46,451 BC and 15,438 OC cases, 15,252 BRCA1 mutation carriers and 73,444 controls and identified ... -
Identification of four novel susceptibility loci for estrogen receptor negative breast cancer
Couch, Fergus J.; Kuchenbaecker, Karoline B.; Michailidou, Kyriaki; Mendoza-Fandino, Gustavo A.; Nord, Silje; Lilyquist, Janna; Olswold, CurtisHallberg, EmilyAgata, SimonaAhsan, HabibulAittomäki, KristiinaAmbrosone, ChristineAndrulis, Irene L.Anton-Culver, HodaArndt, VolkerArun, Banu K.Arver, BritaBarile, MonicaBarkardottir, Rosa B.Barrowdale, DanielBeckmann, LarsBeckmann, Matthias W.Benitez, JavierBlank, Stephanie V.Blomqvist, CarlBogdanova, Natalia V.Bojesen, Stig E.Bolla, Manjeet K.Bonanni, BernardoBrauch, HiltrudBrenner, HermannBurwinkel, BarbaraBuys, Saundra S.Caldes, TrinidadCaligo, Maria A.Canzian, FedericoCarpenter, JaneChang-Claude, JennyChanock, Stephen J.Chung, Wendy K.Claes, Kathleen B. M.Cox, AngelaCross, Simon S.Cunningham, Julie M.Czene, KamilaDaly, Mary B.Damiola, FrancescaDarabi, Hatefde la Hoya, MiguelDevilee, PeterDiez, OrlandDing, Yuan C.Dolcetti, RiccardoDomchek, Susan M.Dorfling, Cecilia M.dos-Santos-Silva, IsabelDumont, MartineDunning, Alison M.Eccles, Diana M.Ehrencrona, HansEkici, Arif B.Eliassen, HeatherEllis, SteveFasching, Peter A.Figueroa, JonineFlesch-Janys, DieterFörsti, AstaFostira, FlorentiaFoulkes, William D.Friebel, TaraFriedman, EitanFrost, DebraGabrielson, MarikeGammon, Marilie D.Ganz, Patricia A.Gapstur, Susan M.Garber, JudyGaudet, Mia M.Gayther, Simon A.Gerdes, Anne-MarieGhoussaini, MayaGiles, Graham G.Glendon, GordGodwin, Andrew K.Goldberg, Mark S.Goldgar, David E.González-Neira, AnnaGreene, Mark H.Gronwald, JacekGuénel, PascalGunter, MarcHaeberle, LotharHaiman, Christopher A.Hamann, UteHansen, Thomas V. O.Hart, StevenHealey, SueHeikkinen, TuomasHenderson, Brian E.Herzog, JosefHogervorst, Frans B. L.Hollestelle, AntoinetteHooning, Maartje J.Hoover, Robert N.Hopper, John L.Humphreys, KeithHunter, David J.Huzarski, TomaszImyanitov, Evgeny N.Isaacs, ClaudineJakubowska, AnnaJames, PaulJanavicius, RamunasJensen, Uffe BirkJohn, Esther M.Jones, MichaelKabisch, MariaKar, SiddarthaKarlan, Beth Y.Khan, SofiaKhaw, Kay-TeeKibriya, Muhammad G.Knight, Julia A.Ko, Yon-DschunKonstantopoulou, IreneKosma, Veli-MattiKristensen, VesselaKwong, AvaLaitman, YaelLambrechts, DietherLazaro, ConxiLee, EunjungMarchand, Loic LeLester, JennyLindblom, AnnikaLindor, NoralaneLindstrom, SaraLiu, JianjunLong, JirongLubinski, JanMai, Phuong L.Makalic, EnesMalone, Kathleen E.Mannermaa, ArtoManoukian, SiranoushMargolin, SaraMarme, FrederikMartens, John W. M.McGuffog, LesleyMeindl, AlfonsMiller, AustinMilne, Roger L.Miron, PenelopeMontagna, MarcoMazoyer, SylvieMulligan, Anna M.Muranen, Taru A.Nathanson, Katherine L.Neuhausen, Susan L.Nevanlinna, HeliNordestgaard, Børge G.Nussbaum, Robert L.Offit, KennethOlah, EdithOlopade, Olufunmilayo I.Olson, Janet E.Osorio, AnaPark, Sue K.Peeters, Petra H.Peissel, BernardPeterlongo, PaoloPeto, JulianPhelan, Catherine M.Pilarski, RobertPoppe, BrucePylkäs, KatriRadice, PaoloRahman, NazneenRantala, JohannaRappaport, ChristineRennert, GadRichardson, AndreaRobson, MarkRomieu, IsabelleRudolph, AnjaRutgers, Emiel J.Sanchez, Maria-JoseSantella, Regina M.Sawyer, Elinor J.Schmidt, Daniel F.Schmidt, Marjanka K.Schmutzler, Rita K.Schumacher, FredrickScott, RodneySenter, LeighaSharma, PriyankaSimard, JacquesSinger, Christian F.Sinilnikova, Olga M.Soucy, PennySouthey, MelissaSteinemann, DorisStenmark-Askmalm, MarieStoppa-Lyonnet, DominiqueSwerdlow, AnthonySzabo, Csilla I.Tamimi, RullaTapper, WilliamTeixeira, Manuel R.Teo, Soo-HwangTerry, Mary B.Thomassen, MadsThompson, DeborahTihomirova, LaimaToland, Amanda E.Tollenaar, Robert A. E. M.Tomlinson, IanTruong, ThérèseTsimiklis, HelenTeulé, AlexTumino, RosarioTung, NadineTurnbull, ClareUrsin, Giskivan Deurzen, Carolien H. M.van Rensburg, Elizabeth J.Varon-Mateeva, RaymondaWang, ZhaomingWang-Gohrke, ShanWeiderpass, ElisabeteWeitzel, Jeffrey N.Whittemore, AliceWildiers, HansWinqvist, RobertYang, Xiaohong R.Yannoukakos, DrakoulisYao, SongZamora, M. PilarZheng, WeiHall, PerKraft, PeterVachon, CelineSlager, SusanChenevix-Trench, GeorgiaPharoah, Paul D. P.Monteiro, Alvaro A. N.García-Closas, MontserratEaston, Douglas F.Antoniou, Antonis C. et al. (Nature Publishing Group, 2016)Common variants in 94 loci have been associated with breast cancer including 15 loci with genome wide significant associations (P<5x10-8) with estrogen receptor (ER)-negative breast cancer and BRCA1-associated breast cancer ... -
Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer
Couch, Fergus J.; Kuchenbaecker, Karoline B.; Michailidou, Kyriaki; Mendoza-Fandino, Gustavo A.; Nord, Silje; Lilyquist, Janna; Olswold, CurtisHallberg, EmilyAgata, SimonaAhsan, HabibulAittomäki, KristiinaAmbrosone, ChristineAndrulis, Irene L.Anton-Culver, HodaArndt, VolkerArun, Banu K.Arver, BritaBarile, MonicaBarkardottir, Rosa B.Barrowdale, DanielBeckmann, LarsBeckmann, Matthias W.Benitez, JavierBlank, Stephanie V.Blomqvist, CarlBogdanova, Natalia V.Bojesen, Stig E.Bolla, Manjeet K.Bonanni, BernardoBrauch, HiltrudBrenner, HermannBurwinkel, BarbaraBuys, Saundra S.Caldes, TrinidadCaligo, Maria A.Canzian, FedericoCarpenter, JaneChang-Claude, JennyChanock, Stephen J.Chung, Wendy K.Claes, Kathleen B. M.Cox, AngelaCross, Simon S.Cunningham, Julie M.Czene, KamilaDaly, Mary B.Damiola, FrancescaDarabi, Hatefde la Hoya, MiguelDevilee, PeterDiez, OrlandDing, Yuan C.Dolcetti, RiccardoDomchek, Susan M.Dorfling, Cecilia M.dos-Santos-Silva, IsabelDumont, MartineDunning, Alison M.Eccles, Diana M.Ehrencrona, HansEkici, Arif B.Eliassen, HeatherEllis, SteveFasching, Peter A.Figueroa, JonineFlesch-Janys, DieterFörsti, AstaFostira, FlorentiaFoulkes, William D.Friebel, TaraFriedman, EitanFrost, DebraGabrielson, MarikeGammon, Marilie D.Ganz, Patricia A.Gapstur, Susan M.Garber, JudyGaudet, Mia M.Gayther, Simon A.Gerdes, Anne-MarieGhoussaini, MayaGiles, Graham G.Glendon, GordGodwin, Andrew K.Goldberg, Mark S.Goldgar, David E.González-Neira, AnnaGreene, Mark H.Gronwald, JacekGuénel, PascalGunter, MarcHaeberle, LotharHaiman, Christopher A.Hamann, UteHansen, Thomas V. O.Hart, StevenHealey, SueHeikkinen, TuomasHenderson, Brian E.Herzog, JosefHogervorst, Frans B. L.Hollestelle, AntoinetteHooning, Maartje J.Hoover, Robert N.Hopper, John L.Humphreys, KeithHunter, David J.Huzarski, TomaszImyanitov, Evgeny N.Isaacs, ClaudineJakubowska, AnnaJames, PaulJanavicius, RamunasJensen, Uffe BirkJohn, Esther M.Jones, MichaelKabisch, MariaKar, SiddharthaKarlan, Beth Y.Khan, SofiaKhaw, Kay-TeeKibriya, Muhammad G.Knight, Julia A.Ko, Yon-DschunKonstantopoulou, IreneKosma, Veli-MattiKristensen, VesselaKwong, AvaLaitman, YaelLambrechts, DietherLazaro, ConxiLee, EunjungLe Marchand, LoicLester, JennyLindblom, AnnikaLindor, NoralaneLindstrom, SaraLiu, JianjunLong, JirongLubinski, JanMai, Phuong L.Makalic, EnesMalone, Kathleen E.Mannermaa, ArtoManoukian, SiranoushMargolin, SaraMarme, FrederikMartens, John W. M.McGuffog, LesleyMeindl, AlfonsMiller, AustinMilne, Roger L.Miron, PenelopeMontagna, MarcoMazoyer, SylvieMulligan, Anna M.Muranen, Taru A.Nathanson, Katherine L.Neuhausen, Susan L.Nevanlinna, HeliNordestgaard, Børge G.Nussbaum, Robert L.Offit, KennethOlah, EdithOlopade, Olufunmilayo I.Olson, Janet E.Osorio, AnaPark, Sue K.Peeters, Petra H.Peissel, BernardPeterlongo, PaoloPeto, JulianPhelan, Catherine M.Pilarski, RobertPoppe, BrucePylkäs, KatriRadice, PaoloRahman, NazneenRantala, JohannaRappaport, ChristineRennert, GadRichardson, AndreaRobson, MarkRomieu, IsabelleRudolph, AnjaRutgers, Emiel J.Sanchez, Maria-JoseSantella, Regina M.Sawyer, Elinor J.Schmidt, Daniel F.Schmidt, Marjanka K.Schmutzler, Rita K.Schumacher, FredrickScott, RodneySenter, LeighaSharma, PriyankaSimard, JacquesSinger, Christian F.Sinilnikova, Olga M.Soucy, PennySouthey, MelissaSteinemann, DorisStenmark-Askmalm, MarieStoppa-Lyonnet, DominiqueSwerdlow, AnthonySzabo, Csilla I.Tamimi, RullaTapper, WilliamTeixeira, Manuel R.Teo, Soo-HwangTerry, Mary B.Thomassen, MadsThompson, DeborahTihomirova, LaimaToland, Amanda E.Tollenaar, Robert A. E. M.Tomlinson, IanTruong, ThérèseTsimiklis, HelenTeulé, AlexTumino, RosarioTung, NadineTurnbull, ClareUrsin, Giskivan Deurzen, Carolien H. M.van Rensburg, Elizabeth J.Varon-Mateeva, RaymondaWang, ZhaomingWang-Gohrke, ShanWeiderpass, ElisabeteWeitzel, Jeffrey N.Whittemore, AliceWildiers, HansWinqvist, RobertYang, Xiaohong R.Yannoukakos, DrakoulisYao, SongZamora, M. PilarZheng, WeiHall, PerKraft, PeterVachon, CelineSlager, SusanChenevix-Trench, GeorgiaPharoah, Paul D. P.Monteiro, Alvaro A. N.García-Closas, MontserratEaston, Douglas F.Antoniou, Antonis C. et al. (Nature Publishing Group, 2016-04-27)Common variants in 94 loci have been associated with breast cancer including 15 loci with genome-wide significant associations (P<5 × 10$^{−8}$) with oestrogen receptor (ER)-negative breast cancer and BRCA1-associated ... -
Identification of independent association signals and putative functional variants for breast cancer risk through fine-scale mapping of the 12p11 locus
Zeng, Chenjie; Guo, Xingyi; Long, Jirong; Kuchenbaecker, Karoline B.; Droit, Arnaud; Michailidou, Kyriaki; Ghoussaini, MayaKar, SiddharthaFreeman, AdamHopper, John L.Milne, Roger L.Bolla, Manjeet K.Wang, QinDennis, JoeAgata, SimonaAhmed, ShahanaAittomäki, KristiinaAndrulis, Irene L.Anton-Culver, HodaAntonenkova, Natalia N.Arason, AdalgeirArndt, VolkerArun, Banu K.Arver, BritaBacot, FrancoisBarrowdale, DanielBaynes, CarolineBeeghly-Fadiel, AliciaBenitez, JavierBermisheva, MarinaBlomqvist, CarlBlot, William J.Bogdanova, Natalia V.Bojesen, Stig E.Bonanni, BernardoBorresen-Dale, Anne-LiseBrand, Judith S.Brauch, HiltrudBrennan, PaulBrenner, HermannBroeks, AnnegienBrüning, ThomasBurwinkel, BarbaraBuys, Saundra S.Cai, QiuyinCaldes, TrinidadCampbell, IanCarpenter, JaneChang-Claude, JennyChoi, Ji-YeobClaes, Kathleen B. M.Clarke, ChristineCox, AngelaCross, Simon S.Czene, KamilaDaly, Mary B.de la Hoya, MiguelDe Leeneer, KimDevilee, PeterDiez, OrlandDomchek, Susan M.Doody, MicheleDorfling, Cecilia M.Dörk, Thilodos-Santos-Silva, IsabelDumont, MartineDwek, MiriamDworniczak, BerndEgan, KathleenEilber, UrsulaEinbeigi, ZakariaEjlertsen, BentEllis, SteveFrost, DebraLalloo, FionaEMBRACE2Fasching, Peter A.Figueroa, JonineFlyger, HenrikFriedlander, MichaelFriedman, EitanGambino, GaetanaGao, Yu-TangGarber, JudyGarcía-Closas, MontserratGehrig, AndreaDamiola, FrancescaLesueur, FabienneMazoyer, SylvieStoppa-Lyonnet, DominiqueGEMO StudyGiles, Graham G.Godwin, Andrew K.Goldgar, David E.González-Neira, AnnaGreene, Mark H.Guénel, PascalHaeberle, LotharHaiman, Christopher A.Hallberg, EmilyHamann, UteHansen, Thomas V. O.Hart, StevenHartikainen, Jaana M.Hartman, MikaelHassan, NorhashimahHealey, SueHogervorst, Frans B. L.Verhoef, SennoHEBON106Hendricks, Carolyn B.Hillemanns, PeterHollestelle, AntoinetteHulick, Peter J.Hunter, David J.Imyanitov, Evgeny N.Isaacs, ClaudineIto, HidemiJakubowska, AnnaJanavicius, RamunasJaworska-Bieniek, KatarzynaJensen, Uffe BirkJohn, Esther M.Beauparlant, Charles JolyJones, MichaelKabisch, MariaKang, DaeheeKarlan, Beth Y.Kauppila, SailaKerin, Michael J.Khan, SofiaKhusnutdinova, ElzaKnight, Julia A.Konstantopoulou, IreneKraft, PeterKwong, AvaLaitman, YaelLambrechts, DietherLazaro, ConxiMarchand, Loic LeLee, Chuen NengLee, Min HyukLester, JennyLi, JingmeiLiljegren, AnnelieLindblom, AnnikaLophatananon, ArtitayaLubinski, JanMai, Phuong L.Mannermaa, ArtoManoukian, SiranoushMargolin, SaraMarme, FrederikMatsuo, KeitaroMcGuffog, LesleyMeindl, AlfonsMenegaux, FlorenceMontagna, MarcoMuir, KennethMulligan, Anna MarieNathanson, Katherine L.Neuhausen, Susan L.Nevanlinna, HeliNewcomb, Polly A.Nord, SiljeNussbaum, Robert L.Offit, KennethOlah, EdithOlopade, Olufunmilayo I.Olswold, CurtisOsorio, AnaPapi, LauraPark-Simon, Tjoung-WonPaulsson-Karlsson, YlvaPeeters, StephaniePeissel, BernardPeterlongo, PaoloPeto, JulianPfeiler, GeorgPhelan, Catherine M.Presneau, NadegeRadice, PaoloRahman, NazneenRamus, Susan J.Rashid, Muhammad UsmanRennert, GadRhiem, KerstinRudolph, AnjaSalani, RituSangrajrang, SuleepornSawyer, Elinor J.Schmidt, Marjanka KSchmutzler, Rita K.Schoemaker, Minouk J.Schürmann, PeterSeynaeve, CarolineShen, Chen-YangShrubsole, Martha J.Shu, Xiao-OuSigurdson, AliceSinger, Christian F.Slager, SusanSoucy, PennySouthey, MelissaSteinemann, DorisSwerdlow, AnthonySzabo, Csilla I.Tchatchou, SandrineTeixeira, Manuel R.Teo, Soo H.Terry, Mary BethTessier, Daniel C.Teulé, AlexThomassen, MadsTihomirova, LaimaTischkowitz, MarcToland, Amanda E.Tung, NadineTurnbull, Clarevan den Ouweland, Ans M. W.van Rensburg, Elizabeth J.ven den Berg, DavidVijai, JosephWang-Gohrke, ShanWeitzel, Jeffrey N.Whittemore, Alice S.Winqvist, RobertWong, Tien Y.Wu, Anna H.Yannoukakos, DrakoulisYu, Jyh-CherngPharoah, Paul D. P.Hall, PerChenevix-Trench, GeorgiaKConFabAOCS InvestigatorsDunning, Alison M.Simard, JacquesCouch, Fergus J.Antoniou, Antonis C.Easton, Douglas F.Zheng, Wei et al. (BioMed Central, 2016)Background Multiple recent genome-wide association studies (GWAS) have identified a single nucleotide polymorphism (SNP), rs10771399, at 12p11 that is associated with breast cancer risk. Method We performed a ... -
Identification of six new susceptibility loci for invasive epithelial ovarian cancer
Kuchenbaecker, Karoline B.; Ramus, Susan J.; Tyrer, Jonathan; Lee, Andrew; Shen, Howard C.; Beesley, Jonathan; Lawrenson, KateMcGuffog, LesleyHealey, SueLee, Janet M.Spindler, Tassja J.Lin, Yvonne G.Pejovic, TanjaBean, YukieLi, QiyuanCoetzee, SimonHazelett, DennisMiron, AlexanderSouthey, MelissaTerry, Mary BethGoldgar, David E.Buys, Saundra S.Janavicius, RamunasDorfling, Cecilia M.Rensburg, Elizabeth J. vanNeuhausen, Susan L.Ding, Yuan ChunHansen, Thomas V. O.Jonson, LarsGerdes, Anne-MarieEjlertsen, BentBarrowdale, DanielDennis, JoeBenitez, JavierOsorio, AnaGarcia, Maria JoseKomenaka, IanWeitzel, Jeffrey N.Ganschow, PamelaPeterlongo, PaoloBernard, LorisViel, AlessandraBonanni, BernardoPeissel, BernardManoukian, SiranoushRadice, PaoloPapi, LauraOttini, LauraFostira, FlorentiaKonstantopoulou, IreneGarber, JudyFrost, DebraPerkins, JoPlatte, RadkaEllis, SteveEMBRACEGodwin, Andrew K.Schmutzler, Rita KatharinaMeindl, AlfonsEngel, ChristophSutter, ChristianSinilnikova, Olga M.GEMO Study CollaboratorsDamiola, FrancescaMazoyer, SylvieStoppa-Lyonnet, DominiqueClaes, KathleenLeeneer, Kim DeKirk, JudyRodriguez, Gustavo C.Piedmonte, MarionO'Malley, David M.Hoya, Miguel de laCaldes, TrinidadAittomaki, KristiinaNevanlinna, HeliCollee, J. MargrietRookus, Matti A.Oosterwijk, Jan C.Breast Cancer Family RegistryTihomirova, LaimaTung, NadineHamann, UteIsaccs, ClaudineTischkowitz, MarcImyanitov, Evgeny N.Caligo, Maria A.Campbell, Ian G.Hogervorst, Frans B. L.HEBONOlah, EdithDiez, OrlandBlanco, IgnacioBrunet, JoanLazaro, ConxiPujana, Miquel AngelJakubowska, AnnaGronwald, JacekLubinski, JanSukiennicki, GrzegorzBarkardottir, Rosa B.Plante, MarieSimard, JacquesSoucy, PennyMontagna, MarcoTognazzo, SilviaTeixeira, Manuel R.KConFab InvestigatorsPankratz, Vernon S.Wang, XianshuLindor, NoralaneSzabo, Csilla I.Kauff, NoahVijai, JosephAghajanian, Carol A.Pfeiler, GeorgBerger, AndreasSinger, Christian F.Tea, Muy-KhengPhelan, Catherine M.Greene, Mark H.Mai, Phuong L.Rennert, GadMulligan, Anna MarieTchatchou, SandrineAndrulis, Irene L.Glendon, GordToland, Amanda EwartJensen, Uffe BirkKruse, Torben A.Thomassen, MadsBojesen, AndersZidan, JamalFriedman, EitanLaitman, YaelSoller, MariaLiljegren, AnnelieArver, BritaEinbeigi, ZakariaStenmark-Askmalm, MarieOlopade, Olufunmilayo I.Nussbaum, Robert L.Rebbeck, Timothy R.Nathanson, Katherine L.Domchek, Susan M.Lu, Karen H.Karlan, Beth Y.Walsh, ChristineLester, JennyAustralian Cancer Study (Ovarian Cancer Investigators)Australian Ovarian Cancer Study GroupHein, AlexanderEkici, Arif B.Beckmann, Matthias W.Fasching, Peter A.Lambrechts, DietherNieuwenhuysen, Els vanVergote, IgnaceLambrechts, SandrinaDicks, EdDoherty, Jennifer A.Wicklund, Kristine G.Rossing, Mary AnneRudolph, AnjaChang-Claude, JennyWang-Gohrke, ShanEilber, UrsulaMoysich, Kirsten B.Odunsi, KunleSucheston, LaraLele, ShashiWilkens, Lynne R.Goodman, Marc T.Thompson, Pamela J.Shvetsov, Yurii B.Runnebaum, Ingo B.Durst, MatthiasHillemanns, PeterDork, ThiloAntonenkova, NataliaBogdanova, NataliaLeminen, ArtoPelttari, Liisa M.Butzow, RalfModugno, FrancesmaryKelley, Joseph L.Edwards, Robert P.Ness, Roberta B.Bois, Andreas duHeitz, FlorianSchwaab, IraHarter, PhilippMatsuo, KeitaroHosono, SatoyoOrsulic, SandraJensen, AllanKjaer, Susanne KrugerHogdall, EstridHasmad, Hanis NazihahAzmi, Mat Adenan NoorTeo, Soo-HwangWoo, Yin-LingFridley, Brooke L.Goode, Ellen L.Cunningham, Julie M.Vierkant, Robert A.Bruinsma, FionaGiles, Graham G.Liang, DongHildebrandt, Michelle A. T.Wu, XifengLevine, Douglas A.Bisogna, MariaBerchuck, AndrewIversen, Edwin S.Schildkraut, Joellen M.Concannon, PatrickWeber, Rachel PalmieriCramer, Daniel W.Terry, Kathryn L.Poole, Elizabeth M.Tworoger, Shelley S.Bandera, Elisa V.Orlow, IreneOlson, Sara H.Krakstad, CamillaSalvesen, Helga B.Tangen, Ingvild L.Bjorge, LineAltena, Anne M. vanAben, Katja K. H.Kiemeney, Lambertus A.Massuger, Leon F. A. G.Kellar, MelissaBrooks-Wilson, AngelaKelemen, Linda E.Cook, Linda S.Le, Nhu D.Cybulski, CezaryYang, HannahLissowska, JolantaBrinton, Louise A.Wentzensen, NicolasHogdall, ClausLundvall, LeneNedergaard, LotteBaker, HelenSong, HonglinEccles, DianaMcNeish, IanPaul, JamesCarty, KarenSiddiqui, NadeemGlasspool, RosalindWhittemore, Alice S.Rothstein, Joseph H.McGuire, ValerieSieh, WeivaJi, Bu-TianZheng, WeiShu, Xiao-OuGao, Yu-TangRosen, BarryRisch, Harvey A.McLaughlin, John R.Narod, Steven A.Monteiro, Alvaro N.Chen, AnnLin, Hui-YiPermuth-Wey, JennySellers, Thomas A.Tsai, Ya-YuChen, ZhihuaZiogas, ArgyriosAnton-Culver, HodaGentry-Maharaj, AleksandraMenon, UshaHarrington, PatriciaLee, Alice W.Wu, Anna H.Pearce, Celeste L.Coetzee, GerryPike, Malcolm C.Dansonka-Mieszkowska, AgnieszkaTimorek, AgnieszkaRzepecka, Iwona K.Kupryjanczyk, JolantaFreedman, MattNoushmehr, HoutanEaston, Douglas F.Offit, KennethCouch, Fergus J.Gayther, SimonPharoah, Paul D. P.Antoniou, Antonis C.Chenevix-Trench, GeorgiaConsortium of Investigators of Modifiers of BRCA1 and BRCA2 et al. (2015-01-12)Genome-wide association studies (GWAS) have identified 12 epithelial ovarian cancer (EOC) susceptibility alleles. The pattern of association at these loci is consistent in BRCA1 and BRCA2 mutation carriers who are at high ...