Now showing items 1-2 of 2

    • Mechanism of eIF6 release from the nascent 60S ribosomal subunit 

      Weis, Félix; Giudice, Emmanuel; Churcher, Mark; Jin, Li; Hilcenko, Christine; Wong, Chi C; Traynor, David et al. (Nature Publishing Group, 2015-10-19)
      SBDS protein (deficient in the inherited leukemia-predisposition disorder Shwachman-Diamond syndrome) and the GTPase EFL1 (an EF-G homolog) activate nascent 60S ribosomal subunits for translation by catalyzing eviction of ...
    • On the effects of cycloheximide on cell motility and polarisation in Dictyostelium discoideum 

      Clotworthy, Margaret; Traynor, David (2006-01-24)
      Abstract Background Cycloheximide is a protein synthesis inhibitor that acts specifically on the 60S subunit of eukaryotic ribosomes. It has previously been shown that a short incubation of Dictyostelium discoideum amoebae ...