Now showing items 1-20 of 27

    • Adiposity, hormone replacement therapy use and breast cancer risk by age and hormone receptor status: a large prospective cohort study 

      Ritte, Rebecca; Lukanova, Annekatrin; Berrino, Franco; Dossus, Laure; Tjønneland, Anne; Olsen, Anja; Overvad, Thure F et al. (2012-05-14)
      Abstract Introduction Associations of hormone-receptor positive breast cancer with excess adiposity are reasonably well characterized; however, uncertainty remains regarding the association of body mass index (BMI) with ...
    • The association of coffee intake with liver cancer risk is mediated by biomarkers of inflammation and hepatocellular injury: data from the European Prospective Investigation into Cancer and Nutrition 

      Aleksandrova, Krasimira; Bamia, Christina; Drogan, Dagmar; Lagiou, Pagona; Trichopoulou, Antonia; Jenab, Mazda; Fedirko, Veronika et al. (American Society for Nutrition, 2015-11-11)
      BACKGROUND: Higher coffee intake has been purportedly related to a lower risk of liver cancer. However, it remains unclear whether this association may be accounted for by specific biological mechanisms. OBJECTIVE: ...
    • The association of education with body mass index and waist circumference in the EPIC-PANACEA study 

      Hermann, Silke; Rohrmann, Sabine; Linseisen, Jakob; May, Anne M; Kunst, Anton; Besson, Herve; Romaguera, Dora et al. (2011-03-17)
      Abstract Background To examine the association of education with body mass index (BMI) and waist circumference (WC) in the European Prospective Investigation into Cancer and Nutrition (EPIC). Method This study included ...
    • Circulating copper and zinc levels and risk of hepatobiliary cancers in Europeans. 

      Stepien, Magdalena; Hughes, David J; Hybsier, Sandra; Bamia, Christina; Tjønneland, Anne; Overvad, Kim; Affret, Aurélie et al. (2017-02-02)
      BACKGROUND: Copper and zinc are essential micronutrients and cofactors of many enzymatic reactions that may be involved in liver-cancer development. We aimed to assess pre-diagnostic circulating levels of copper, zinc and ...
    • Circulating Osteopontin and Prediction of Hepatocellular Carcinoma Development in a Large European Population 

      Duarte-Salles, Talita; Misra, Sandeep; Stepien, Magdalena; Plymoth, Amelie; Muller, David C; Overvad, Kim; Olsen, Anja et al. (American Association for Cancer Research, 2016-06-23)
      We previously identified osteopontin (OPN) as a promising marker for the early detection of hepatocellular carcinoma (HCC). In this study, we investigated the association between pre-diagnostic circulating OPN levels and ...
    • Coffee Drinking and Mortality in 10 European Countries: A Multinational Cohort Study 

      Gunter, Marc J; Murphy, Neil; Cross, Amanda J; Dossus, Laure; Dartois, Laureen; Fagherazzi, Guy; Kaaks, Rudolf et al. (American College of Physicians, 2017-08-15)
      Background: The relationship between coffee consumption and mortality in diverse European populations with variable coffee preparation methods is unclear. Objective: To examine whether coffee consumption is associated with ...
    • Correlates of circulating ovarian cancer early detection markers and their contribution to discrimination of early detection models: results from the EPIC cohort 

      Fortner, Renée T; Vitonis, Allison F; Schock, Helena; Hüsing, Anika; Johnson, Theron; Fichorova, Raina N; Fashemi, Titilayo et al. (2017-03-20)
      Abstract Background Ovarian cancer early detection markers CA125, CA15.3, HE4, and CA72.4 vary between healthy women, limiting their utility for screening. ...
    • Determinants of non- response to a second assessment of lifestyle factors and body weight in the EPIC-PANACEA study 

      May, Anne M; Adema, Lotte E; Romaguera, Dora; Vergnaud, Anne-Claire; Agudo, Antonio; Ekelund, Ulf Mikael; Steffen, Annika et al. (2012-09-24)
      Abstract Background This paper discusses whether baseline demographic, socio-economic, health variables, length of follow-up and method of contacting the participants predict non-response to the invitation for a second ...
    • Diet Quality Scores and Prediction of All-Cause, Cardiovascular and Cancer Mortality in a Pan-European Cohort Study 

      Lassale, Camille; Gunter, Marc J; Romaguera, Dora; Peelen, Linda M; Van, der Schouw Yvonne T; Beulens, Joline WJ; Freisling, Heinz et al. (Public Library of Science, 2016-07-13)
      Scores of overall diet quality have received increasing attention in relation to disease aetiology; however, their value in risk prediction has been little examined. The objective was to assess and compare the association ...
    • Dietary flavonoid intake and colorectal cancer risk in the European prospective investigation into cancer and nutrition (EPIC) cohort. 

      Zamora-Ros, Raul; Barupal, Dinesh K; Rothwell, Joseph A; Jenab, Mazda; Fedirko, Veronika; Romieu, Isabelle; Aleksandrova, Krasimira et al. (John Wiley & Sons Inc., 2017-04)
      Flavonoids have been shown to inhibit colon cancer cell proliferation in vitro and protect against colorectal carcinogenesis in animal models. However, epidemiological evidence on the potential role of flavonoid intake in ...
    • Dietary Polyphenols in the Aetiology of Crohn's Disease and Ulcerative Colitis—A Multicenter European Prospective Cohort Study (EPIC) 

      Lu, Yunxia; Zamora-Ros, Raul; Chan, Simon; Cross, Amanda J; Ward, Heather; Jakszyn, Paula; Luben, Robert et al. (Oxford University Press, 2017-12-01)
      Background: Oxidative stress may be involved in the aetiology of inflammatory bowel disease and whether dietary polyphenols, which possess antioxidants properties, prevent its development is unknown. Methods: A total ...
    • Flavonoid and lignan intake and pancreatic cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort 

      Molina-Montes, Esther; Sánchez, María-José; Zamora-Ros, Raul; Bueno-de-Mesquita, HB(as); Wark, Petra A; Obon-Santacana, Mireia; Kühn, Tilman et al. (Wiley, 2016)
      Despite the potential cancer preventive effects of flavonoids and lignans, their ability to reduce pancreatic cancer risk has not been demonstrated in epidemiological studies. Our aim was to examine the association between ...
    • The INSIG2 rs7566605 polymorphism is not associated with body mass index and breast cancer risk 

      Campa, Daniele; Husing, Anika; McKay, James D; Sinilnikova, Olga M; Vogel, Ulla; Tjonneland, Anne; Overvad, Kim et al. (2010-10-18)
      Abstract Background The single nucleotide polymorphism rs7566605, located in the promoter of the INSIG2 gene, has been the subject of a strong scientific effort aimed to elucidate its possible association with body mass ...
    • Lung cancers attributable to environmental tobacco smoke and air pollution in non-smokers in different European countries: a prospective study 

      Vineis, Paolo; Hoek, Gerard; Krzyzanowski, Michal; Vigna-Taglianti, Federica; Veglia, Fabrizio; Airoldi, Luisa; Overvad, Kim et al. (2007-02-15)
      Abstract Background Several countries are discussing new legislation on the ban of smoking in public places, and on the acceptable levels of traffic-related air pollutants. It is therefore useful to estimate the burden of ...
    • Main nutrient patterns and colorectal cancer risk in the European Prospective Investigation into Cancer and Nutrition study. 

      Moskal, Aurélie; Freisling, Heinz; Byrnes, Graham; Assi, Nada; Fahey, Michael T; Jenab, Mazda; Ferrari, Pietro et al. (2016-11)
    • Meat consumption and mortality - results from the European Prospective Investigation into Cancer and Nutrition 

      Rohrmann, Sabine; Overvad, Kim; Bueno-de-Mesquita, HB; Jakobsen, Marianne U; Egeberg, Rikke; Tjønneland, Anne; Nailler, Laura et al. (2013-03-07)
      Abstract Background Recently, some US cohorts have shown a moderate association between red and processed meat consumption and mortality supporting the results of previous studies among vegetarians. The aim of this study ...
    • Modifiable causes of premature death in middle-age in Western Europe: results from the EPIC cohort study. 

      Muller, David C; Murphy, Neil; Johansson, Mattias; Ferrari, Pietro; Tsilidis, Konstantinos K; Boutron-Ruault, Marie-Christine; Clavel, Francoise et al. (BioMed Central, 2016-06-14)
      BACKGROUND: Life expectancy is increasing in Europe, yet a substantial proportion of adults still die prematurely before the age of 70 years. We sought to estimate the joint and relative contributions of tobacco smoking, ...
    • Osteoprotegerin and breast cancer risk by hormone receptor subtype: a nested case-control study in the EPIC cohort 

      Fortner, Renée T; Sarink, Danja; Schock, Helena; Johnson, Theron; Tjønneland, Anne; Olsen, Anja; Overvad, Kim et al. (2017-02-08)
      Abstract Background Circulating osteoprotegerin (OPG), a member of the receptor activator of nuclear factor kappa-B (RANK) axis, may influence breast cancer risk via its role ...
    • Physical Activity and all-cause mortality across levels of general and abdominal adiposity: The European Prospective Investigation into Cancer and Nutrition Study (EPIC) 

      Ekelund, Ulf Mikael; Ward, Heather A; Norat, Teresa; Luan, Jian'an; May, Anne M; Weiderpass, Elisabete; Sharp, Stephen John et al. (American Society for Nutrition, 2015-01-14)
      Background: The higher risk of death resulting from excess adiposity may be attenuated by physical activity (PA). However, the theoretical number of deaths reduced by eliminating physical inactivity compared with overall ...
    • Pre-diagnostic concordance with the WCRF/AICR guidelines and survival in European colorectal cancer patients: a cohort study 

      Romaguera, Dora; Ward, Heather; Wark, Petra A; Vergnaud, Anne-Claire; Peeters, Petra H; van, Gils Carla H; Ferrari, Pietro et al. (2015-05-07)
      Abstract Background Cancer survivors are advised to follow lifestyle recommendations on diet, physical activity, and body fatness proposed by the World Cancer Research ...