Now showing items 1-8 of 8

    • Association between plasma phospholipid saturated fatty acids and metabolic markers of lipid, hepatic, inflammation and glycaemic pathways in eight European countries: a cross-sectional analysis in the EPIC-InterAct study 

      Zheng, Ju-Sheng; Sharp, Stephen J; Imamura, Fumiaki; Koulman, Albert; Schulze, Matthias B; Ye, Zheng; Griffin, Jules et al. (2017-11-17)
      Abstract Background Accumulating evidence suggests that individual circulating saturated fatty acids (SFAs) are heterogeneous in their associations with cardio-metabolic ...
    • Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study. 

      Winkler, Thomas W; Justice, Anne E; Graff, Mariaelisa; Barata, Llilda; Feitosa, Mary F; Chu, Su; Czajkowski, Jacek et al. (2016-06-29)
    • Gender and the double burden of economic and social disadvantages on healthy eating: cross-sectional study of older adults in the EPIC-Norfolk cohort 

      Conklin, Annalijn I; Forouhi, Nita G; Surtees, Paul; Wareham, Nicholas J; Monsivais, Pablo (2015-07-22)
      Abstract Background Multiple economic factors and social relationships determine dietary behaviours, but the inter-relations between determinants is unknown. Whether women and ...
    • A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease 

      Scott, Robert; Freitag, Daniel F; Li, Li; Chu, Audrey Y; Surendran, Praveen; Young, Robin; Grarup, Niels et al. (American Association for the Advancement of Science, 2016-06-01)
      Regulatory authorities have indicated that new drugs to treat type 2 diabetes (T2D) should not be associated with an unacceptable increase in cardiovascular risk. Human genetics may be able to guide development of antidiabetic ...
    • Longitudinal association of C-reactive protein and Haemoglobin A1c over 13 years: the European Prospective Investigation into Cancer - Norfolk study 

      Ahmadi-Abhari, Sara; Kaptoge, Stephen; Luben, Robert N; Wareham, Nicholas J; Khaw, Kay-Tee (2015-05-22)
      Abstract Background Type-2 diabetes is associated with systemic inflammation and higher C-reactive protein (CRP) levels. However, the longitudinal association of CRP and ...
    • Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes. 

      Malik, Rainer; Chauhan, Ganesh; Traylor, Matthew Stephen; Sargurupremraj, Muralidharan; Okada, Yukinori; Mishra, Aniket; Rutten-Jacobs, Loes Carola et al. (Springer Nature, 2018-04)
      Stroke has multiple etiologies but the underlying genes and pathways are largely unknown. We conducted a multi-ancestry genome-wide association meta-analysis in 521,612 individuals (67,162 cases and 454,450 controls) and ...
    • Prospective association of the Mediterranean diet with cardiovascular disease incidence and mortality and its population impact in a non-Mediterranean population: the EPIC-Norfolk study 

      Tong, Tammy Y N; Wareham, Nicholas J; Khaw, Kay-Tee; Imamura, Fumiaki; Forouhi, Nita G (2016-09-29)
      Abstract Background Despite convincing evidence in the Mediterranean region, the cardiovascular benefit of the Mediterranean diet is not well established in non-Mediterranean ...
    • Residential neighbourhood greenspace is associated with reduced risk of incident diabetes in older people: a prospective cohort study 

      Dalton, Alice M; Jones, Andrew P; Sharp, Stephen J; Cooper, Andrew J M; Griffin, Simon; Wareham, Nicholas J (2016-11-18)
      Abstract Background Three cross sectional studies suggest that neighbourhood greenspace may protect against incident diabetes. This study uses data from a longitudinal study ...