Now showing items 1-2 of 2

    • High-resolution aCGH and expression profiling identifies a novel genomic subtype of ER negative breast cancer 

      Chin, Suet-Feung; Teschendorff, Andrew E.; Marioni, John C.; Wang, Yanzhong; Barbosa-Morais, Nuno L.; Thorne, Natalie P.; Costa, Jose L. et al. (2007-10-07)
      Abstract Background The characterization of copy number alteration patterns in breast cancer requires high-resolution genome-wide profiling of a large panel of tumor specimens. To date, most genome-wide array comparative ...
    • Sequencing Structural Variants in Cancer for Precision Therapeutics 

      Macintyre, Geoff; Ylstra, Bauke; Brenton, James D. (Cell/Elsevier, 2016-07-29)
      The identification of mutations that guide therapy selection for patients with cancer is now routine in many clinical centres. The majority of assays used for solid tumour profiling use DNA sequencing to interrogate somatic ...