Now showing items 2-4 of 4

    • Lst4, the yeast Fnip1/2 orthologue is a DENN-family protein 

      Pacitto, Angela; Ascher, David B.; Wong, Louise H.; Blaszczyk, Beata K.; Nookala, Ravi K.; Zhang, Nianshu; Dokudovskaya, Svetlana et al. (Royal Society, 2015-12-02)
      The folliculin/fnip complex has been demonstrated to play a crucial role in the mechanisms underlying Birt-Hogg-Dubé syndrome, a rare inherited cancer syndrome. Lst4 has been previously proposed to be the Fnip1/2 orthologue ...
    • The genetic control of growth rate: a systems biology study in yeast. 

      Pir, Pinar; Gutteridge, Alex; Wu, Jian; Rash, Bharat; Kell, Douglas B; Zhang, Nianshu; Oliver, Stephen G (2012-01-13)
      Abstract Background Control of growth rate is mediated by tight regulation mechanisms in all free-living organisms since long-term survival depends on adaptation to diverse environmental conditions. The yeast, Saccharomyces ...
    • The yeast GSK-3 homologue Mck1 is a key controller of quiescence entry and chronological lifespan 

      Quan, Zhenzhen; Cao, Lu; Tang, Yingzhi; Yan, Yanchun; Oliver, Stephen George; Zhang, Nianshu (PLOS, 2015-06-16)
      Upon starvation for glucose or any other core nutrient, yeast cells exit from the mitotic cell cycle and acquire a set of G0-specific characteristics to ensure long-term survival. It is not well understood whether or how ...