Browsing by Author "Zhang, Nianshu"

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Starvation signals in yeast are integrated to coordinate metabolic reprogramming and stress response to ensure longevity

Zhang, Nianshu; Cao, L

Studies on replicative and chronological aging in Saccharomyces cerevisiae have greatly advanced our understanding of how longevity is regulated in all eukaryotes. Chronological lifespan (CLS) of yeast is defined as the ...
The yeast GSK-3 homologue Mck1 is a key controller of quiescence entry and chronological lifespan

Quan, Zhenzhen; Cao, Lu; Tang, Yingzhi; Yan, Yanchun; Oliver, Stephen George; Zhang, Nianshu (PLOS, 2015-06-16)

Upon starvation for glucose or any other core nutrient, yeast cells exit from the mitotic cell cycle and acquire a set of G0-specific characteristics to ensure long-term survival. It is not well understood whether or how ...