Now showing items 1-4 of 4

    • Dietary long-chain, but not medium-chain, triglycerides impair exercise performance and uncouple cardiac mitochondria in rats 

      Murray, Andrew J.; Knight, Nicholas S.; Little, Sarah E.; Cochlin, Lowri E.; Clements, Mary; Clarke, Kieran (2011-08-01)
      Abstract Short-term consumption of a high-fat diet impairs exercise capacity in both rats and humans, and increases expression of the mitochondrial uncoupling protein, UCP3, in rodent cardiac and skeletal muscle via ...
    • Nitrate enhances skeletal muscle fatty acid oxidation via a nitric oxide-cGMP-PPAR-mediated mechanism 

      Ashmore, Tom; Roberts, Lee D.; Morash, Andrea J.; Kotwica, Aleksandra O.; Finnerty, John; West, James A.; Murfitt, Steven A. et al. (BioMed Central, 2015-12-22)
      BACKGROUND. Insulin sensitivity in skeletal muscle is associated with metabolic flexibility, including a high capacity to increase fatty acid (FA) oxidation in response to increased lipid supply. Lipid overload, however, ...
    • Nitrate enhances skeletal muscle fatty acid oxidation via a nitric oxide-cGMP-PPAR-mediated mechanism 

      Ashmore, Tom; Roberts, Lee D; Morash, Andrea J; Kotwica, Aleksandra O; Finnerty, John; West, James A; Murfitt, Steven A et al. (2015-12-22)
      Abstract Background Insulin sensitivity in skeletal muscle is associated with metabolic flexibility, including a high capacity to increase fatty acid (FA) oxidation in response ...
    • Novel ketone diet enhances physical and cognitive performance 

      Murray, Andrew J.; Knight, Nicholas S.; Cole, Mark A.; Cochlin, Lowri E.; Carter, Emma; Tchabanenko, Kirill; Pichulik, Tica et al. (Federation of American Societies for Experimental Biology, 2016-08-15)
      Ketone bodies are themost energy-efficient fuel and yieldmoreATP permole of substrate than pyruvate and increase the free energy released from ATP hydrolysis. Elevation of circulating ketones via high-fat, lowcarbohydrate diets ...