Now showing items 1-3 of 3

    • CD133: a Potential Indicator for Differentiation and Prognosis of Human Cholangiocarcinoma 

      Fan, Linni; He, Furong; Liu, Hongxiang; Zhu, Jin; Liu, Yixiong; Yin, Zhiyong; Wang, Lu et al. (2011-07-29)
      Abstract Background CD133 is known to be a cancer stem cell (CSC) marker. However, recent studies have revealed that CD133 is not restricted to CSC but to be expressed not only in human normal tissues but also in some ...
    • KLF2 mutation is the most frequent somatic change in splenic marginal zone lymphoma and identifies a subset with distinct genotype 

      Clipson, Alexandra; Wang, Ming; de Leval, Laurence; Ashton-Key, Margaret; Wotherspoon, Andrew; Vassiliou, George; Bolli, Niccolo et al. (Nature Publishing Group, 2014-11-27)
      To characterise the genetics of splenic marginal zone lymphoma (SMZL), we performed whole exome sequencing of 16 cases and identified novel recurrent inactivating mutations in KLF2, a gene whose deficiency was previously ...
    • The Prognosis of MYC Translocation Positive Diffuse Large B-Cell Lymphoma Depends on The Second Hit 

      Clipson, Alexandra; Barrans, Sharon; Zeng, Naiyan; Crouch, Simon; Grigoropoulos, Nicholas F.; Liu, Hongxiang; Kocialkowski, Sylvia et al. (Wiley, 2015-01-08)
      A proportion of MYC translocation positive diffuse large B-cell lymphomas (DLBCL) harbour a BCL2 and/or BCL6 translocation, known as double-hit DLBCL, and are clinically aggressive. It is unknown whether there are other ...