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    • Molecular effects of Lapatinib in the treatment of HER2 Overexpressing Oesophago-Gastric Adenocarcinoma 

      Silva, Nadeera De; Schulz, Laura; Paterson, Anna; Qain, Wendi; Secrier, Maria; Godfrey, Edmund; Cheow, Heok et al. (Nature Publishing Group, 2015-10-20)
      Background Lapatinib, a dual EGFR and HER2 inhibitor has shown disappointing results in clinical trials of metastatic Oesophago-Gastric Adenocarcinomas (OGA), and in vitro studies suggest that MET, IGFR, and HER3 confer ...