Now showing items 1-5 of 5

    • Association analysis identifies 65 new breast cancer risk loci 

      Michailidou, K; Lindström, S; Dennis, J; Beesley, J; Hui, S; Kar, S; Lemaçon, A et al. (Nature Publishing Group, 2017-10-23)
      Breast cancer risk is influenced by rare coding variants in susceptibility genes, such as BRCA1, and many common, mostly non-coding variants. However, much of the genetic contribution to breast cancer risk remains unknown. ...
    • Association of breast cancer risk with genetic variants showing differential allelic expression: Identification of a novel breast cancer susceptibility locus at 4q21 

      Hamdi, Y; Soucy, P; Adoue, V; Michailidou, Kyriaki; Canisius, S; Lemaçon, A; Droit, A et al. (Impact Journals, 2016-10-21)
      There are significant inter-individual differences in the levels of gene expression. Through modulation of gene expression, $\textit{cis}$-acting variants represent an important source of phenotypic variation. Consequently, ...
    • Common germline polymorphisms associated with breast cancer specific survival 

      Pirie, A; Guo, Qi; Kraft, P; Canisius, S; Eccles, DM; Rahman, N; Nevanlinna, H et al. (2015-04-22)
    • A comprehensive evaluation of interaction between genetic variants and use of menopausal hormone therapy on mammographic density 

      Rudolph, A; Fasching, PA; Behrens, S; Eilber, U; Bolla, Manjeet Kaur; Wang, Qin; Thompson, Deborah Jane et al. (2015-08-16)
    • rs2735383, located at a microRNA binding site in the 3'UTR of NBS1, is not associated with breast cancer risk 

      Liu, J; Lončar, I; Collée, JM; Bolla, MK; Dennis, J; Michailidou, K; Wang, Qin et al. (Nature Publishing Group, 2016-12)
      NBS1, also known as NBN, plays an important role in maintaining genomic stability. Interestingly, rs2735383 G > C, located in a microRNA binding site in the 3'-untranslated region (UTR) of NBS1, was shown to be associated ...