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    • Hoxa9 and Meis1 Cooperatively Induce Addiction to Syk Signaling by Suppressing miR-146a in Acute Myeloid Leukemia 

      Mohr, S; Doebele, C; Comoglio, F; Berg, T; Beck, J; Bohnenberger, H; Alexe, G et al. (Elsevier (Cell Press), 2017-04-10)
      The transcription factor Meis1 drives myeloid leukemogenesis in the context of Hox gene overexpression but is currently considered undruggable. We therefore investigated whether myeloid progenitor cells transformed by Hoxa9 ...