Now showing items 1-4 of 4

    • A common variant at the 14q32 endometrial cancer risk locus activates AKT1 through YY1 binding 

      Painter, Jodie N; Kaufmann, Susanne; O’Mara, Tracy A; Hillman, Kristine M; Sivakumaran, Haran; Darabi, Hatef; Cheng, Timothy HT et al. (2016)
    • A comprehensive assessment of somatic mutation detection in cancer using whole genome sequencing 

      Alioto, Tyler S; Buchhalter, Ivo; Derdak, Sophia; Hutter, Barbara; Eldridge, Matthew D; Hovig, Eivind; Heisler, Lawrence E et al. (2015)
    • Mitochondrial mutations and metabolic adaptation in pancreatic cancer 

      Hardie, Rae-Anne; van Dam, Ellen; Cowley, Mark; Han, Ting-Li; Balaban, Seher; Pajic, Marina; Pinese, Mark et al. (2017-01-30)
      Abstract Background Pancreatic cancer has a five-year survival rate of ~8%, with characteristic molecular heterogeneity and restricted treatment options. Targeting metabolism ...
    • Mutational signatures in esophageal adenocarcinoma define etiologically distinct subgroups with therapeutic relevance 

      Secrier, Maria; Li, Xiaodun; de, Silva Nadeera; Eldridge, Matthew D; Contino, Gianmarco; Bornschein, Jan; MacRae, Shona et al. (2016-09-05)