Now showing items 1-2 of 2

    • Homozygosity and risk of childhood death due to invasive bacterial disease 

      Lyons, Emily J; Amos, William; Berkley, James A; Mwangi, Isaiah; Shafi, Mohammed; Williams, Thomas N; Newton, Charles R et al. (2009-06-12)
      Abstract Background Genetic heterozygosity is increasingly being shown to be a key predictor of fitness in natural populations, both through inbreeding depression, inbred individuals having low heterozygosity, and also ...
    • Polymorphism in a lincRNA Associates with a Doubled Risk of Pneumococcal Bacteremia in Kenyan Children 

      Rautanen, Anna; Pirinen, Matti; Mills, Tara C; Rockett, Kirk A; Strange, Amy; Ndungu, Anne W; Naranbhai, Vivek et al. (Cell/Elsevier, 2016-05-26)
      Bacteremia (bacterial bloodstream infection) is a major cause of illness and death in sub-Saharan Africa but little is known about the role of human genetics in susceptibility. We conducted a genome-wide association study ...