Now showing items 1-10 of 10

    • Chromosomal evolution and phylogeny in the Nullicauda group (Chiroptera, Phyllostomidae): evidence from multidirectional chromosome painting 

      Gomes, Anderson J B; Nagamachi, Cleusa Y; Rodrigues, Luis R R; Ferguson-Smith, Malcolm A; Yang, Fengtang; O’Brien, Patricia C M; Pieczarka, Julio C (2018-04-25)
      Abstract Background The family Phyllostomidae (Chiroptera) shows wide morphological, molecular and cytogenetic variation; many disagreements regarding its phylogeny and taxonomy ...
    • Contrasting origin of B chromosomes in two cervids (Siberian roe deer and grey brocket deer) unravelled by chromosome-specific DNA sequencing 

      Makunin, Alexey I; Kichigin, Ilya G; Larkin, Denis M; O’Brien, Patricia CM; Ferguson-Smith, Malcolm; Yang, Fengtang; Proskuryakova, Anastasiya A et al. (2016-08-11)
      Abstract Background B chromosomes are dispensable and variable karyotypic elements found in some species of animals, plants and fungi. They often originate from duplications ...
    • Expansion of the HSFY gene family in pig lineages 

      Skinner, Benjamin M; Lachani, Kim; Sargent, Carole A; Yang, Fengtang; Ellis, Peter; Hunt, Toby; Fu, Beiyuan et al. (2015-06-09)
      Abstract Background Amplified gene families on sex chromosomes can harbour genes with important biological functions, especially relating to fertility. The Y-linked heat shock ...
    • Expansion of the HSFY gene family in pig lineages 

      Skinner, Benjamin Matthew; Lachani, Kim; Sargent, Carole Anne; Yang, Fengtang; Ellis, Peter; Hunt, Toby; Fu, Beiyuan et al. (BioMed Central, 2015-06-09)
      Background: Amplified gene families on sex chromosomes can harbour genes with important biological functions, especially relating to fertility. The Y-linked heat shock transcription factor (HSFY) family has become amplified ...
    • Flying lemurs - the "flying tree shrews"? Molecular cytogenetic evidence for a Scandentia-Dermoptera sister clade 

      Nie, Wenhui; Fu, Beiyuan; O'Brien, Patricia CM; Wang, Jinhuan; Su, Weiting; Tanomtong, Alongklod; Volobouev, Vitaly et al. (2008-05-01)
      Abstract Background Flying lemurs or Colugos (order Dermoptera) represent an ancient mammalian lineage that contains only two extant species. Although molecular evidence strongly supports that the orders Dermoptera, ...
    • Generation and Characterisation of a $\textit{Pax8}$-CreER$^\text{T2}$ Transgenic Line and a $\textit{Slc22a6}$-CreER$^\text{T2}$ Knock-In Line for Inducible and Specific Genetic Manipulation of Renal Tubular Epithelial Cells 

      Espana-Agusti, Judit; Zou, Xiangang; Wong, Kim; Fu, Beiyuan; Yang, Fengtang; Tuveson, David A; Adams, David J et al. (Public Library of Science, 2016-02-11)
      Genetically relevant mouse models need to recapitulate the hallmarks of human disease by permitting spatiotemporal gene targeting. This is especially important for replicating the biology of complex diseases like cancer, ...
    • Multidirectional chromosome painting substantiates the occurrence of extensive genomic reshuffling within Accipitriformes 

      Nie, Wenhui; O’Brien, Patricia CM; Fu, Beiyuan; Wang, Jinghuan; Su, Weiting; He, Kai; Bed’Hom, Bertrand et al. (2015-09-26)
      Abstract Background Previous cross-species painting studies with probes from chicken (Gallus gallus) chromosomes 1–10 and a paint pool of nineteen microchromosomes have revealed ...
    • The Origins and Vulnerabilities of Two Transmissible Cancers in Tasmanian Devils. 

      Stammnitz, Maximilian; Coorens, Tim HH; Gori, Kevin Charles; Hayes, Dane; Fu, Beiyuan; Wang, Jinhong; Martin-Herranz, Daniel E et al. (Elsevier, 2018-04)
      Transmissible cancers are clonal lineages that spread through populations via contagious cancer cells. Although rare in nature, two facial tumor clones affect Tasmanian devils. Here we perform comparative genetic and ...
    • The pig X and Y Chromosomes: structure, sequence, and evolution 

      Skinner, Benjamin Matthew; Sargent, Carole Anne; Churcher, Carol; Hunt, Toby; Herrero, Javier; Loveland, Jane E; Dunn, Matt et al. (Cold Spring Harbor Laboratory Press, 2015-11-11)
      We have generated an improved assembly and gene annotation of the pig X Chromosome, and a first draft assembly of the pig Y Chromosome, by sequencing BAC and fosmid clones from Duroc animals and incorporating information ...
    • Sequence of a complete chicken BG haplotype shows dynamic expansion and contraction of two gene lineages with particular expression patterns 

      Salomonsen, Jan; Chattaway, John A; Chan, Andrew CY; Parker, Aimée; Huguet, Samuel; Marston, Denise A; Rogers, Sally L et al. (PLOS, 2014-06-05)
      Many genes important in immunity are found as multigene families. The butyrophilin genes are members of the B7 family, playing diverse roles in co-regulation and perhaps in antigen presentation. In humans, a fixed number ...