Now showing items 10793-10812 of 222599

    • ENDEAVOUR: A Scalable SDN Architecture for Real-World IXPs 

      Antichi, Gianni; Castro, I; Chiesa, M; Fernandes, EL; Lapeyrade, R; Koop, D; Han, JH et al. (IEEE, 2017-11-01)
      Innovation in interdomain routing has remained stagnant for over a decade. Recently, IXPs have emerged as economically-advantageous interconnection points for reducing path latencies and exchanging ever increasing traffic ...
    • Endocannabinoids and striatal function: implications for addiction-related behaviours 

      Moreira, Fabricio A; Jupp, Bianca Marie; Belin, David; Dalley, Jeffrey Wayne (Wolters Kluwer, 2014)
      Since the identification and cloning of the major brain expressed cannabinoid receptor almost twenty five years ago research has highlighted the potential of drugs that target the endocannabinoid system for treating ...
    • Endocranial volume is heritable and is associated with longevity and fitness in a wild mammal 

      Logan, Corina Jill; Kruuk, LEB; Stanley, R; Thompson, AM; Clutton-Brock, Timothy Hugh (Royal Society Publishing, 2016-12-14)
      Research on relative brain size in mammals suggests that increases in brain size may generate benefits to survival and costs to fecundity: comparative studies of mammals have shown that interspecific differences in relative ...
    • Endocrine regulation of placental phenotype 

      Fowden, Abigail Lesley; Forhead, Alison Jane; Sferruzzi-Perri, Amanda Nancy; Burton, Graham James; Vaughan, Owen Rhys (Elsevier, 2014-12-03)
      Hormones have an important role in regulating fetal development. They act as environmental signals and integrate tissue growth and differentiation with relation to nutrient availability. While hormones control the developmental ...
    • Endocytosis Mechanism of Nano Metal-organic Frameworks for Drug Delivery 

      Orellana-Tavra, Claudia; Mercado, Sergio A; Fairen-Jimenez, David (Wiley, 2016)
      We have investigated for the first time the pathway of internalization and final fate of a specific metal-organic framework (MOF) in cells. We have based our study on two calcein loaded UiO-66 samples with particles size ...
    • Endogeneity analysis of output synchronization in the current and prospective EMU 

      Arestis, Philip; Phelps, Peter (Wiley, 2015-10-08)
      The sustainability of European economic and monetary union (EMU) remains an important issue in light of existing plans for enlargement. This paper conducts an endogeneity analysis of output synchronization, based on panel ...
    • Endogenous contagion – a panel data analysis 

      Baur, Dirk; Fry, Renee (CFAP, Cambridge Judge Business School, University of Cambridge, 2006)
      This paper proposes a panel data model to analyze contagion in a multivariate framework. The model distinguishes between vulnerability and contagion, and provides a time series of contagion. The most important feature of ...
    • Endogenous Correlation 

      Yang, J.-H. Steffi; Satchell, Stephen E. (Faculty of Economics, 2004-06-16)
      We model endogenous correlation in asset returns via the role of heterogeneous expectations in investor types, and the dynamic impact of imitative learning by investors. Learning is driven by relative performance. In ...
    • Endogenous Market Turbulence 

      Tambakis, Demosthenes N (CFAP, Cambridge Judge Business School, University of Cambridge, 2006-04)
      In this paper I study a nonlinear feedback trading model which can generate stable, unstable, turbulent or chaotic asset returns depending on market conditions. The dynamics are driven by the stochastic price impact of net ...
    • Endogenous miRNA in the green alga Chlamydomonas regulates gene expression through CDS-targeting 

      Chung, Ying-Wen Betty; Deery, Michael John; Groen, A; Howard, J; Baulcombe, David Charles
      MicroRNAs regulate gene expression as part of the RNA-induced silencing complex, for which the sequence identity of the miRNA provides the specificity to the target messenger RNA and the result is target repression. The ...
    • An endogenous nanomineral chaperones luminal antigen and peptidoglycan to intestinal immune cells. 

      Powell, Jonathan Joseph; Thomas-McKay, Emma; Thoree, Vinay; Robertson, Jack; Hewitt, Rachel Elaine; Skepper, Jeremy N; Brown, Andy et al. (2015-04)
    • Endogenous pH-Responsive Nanoparticles with programmable size change for Targeting Tumor Therapy and Imaging Applications 

      Wu, Wei; Luo, Li; Wang, Yi; Wu, Qi; Dai, Han-Bin; Li, Jian-Shu; Durkan, Colm et al.
      Antitumor drug delivery systems ("Nanocarriers") based on nanotechnology have started to demonstrate their efficacy in recent years. The optimum size of these nanocarriers is paramount and must be designed uniquely for ...
    • Endogenous signalling pathways and caged-IP3 evoke Ca2+ puffs at the same abundant immobile intracellular sites 

      Keebler, MV; Taylor, Colin William
      The building blocks for intracellular Ca2+ signals evoked by inositol 1,4,5-trisphosphate receptors (IP3Rs) are Ca2+ puffs, transient focal increases in Ca2+ concentration that reflect the opening of a small clusters of ...
    • Endoglin potentiates nitric oxide synthesis to enhance definitive hematopoiesis 

      Nasrallah, Rabab; Knezevic, Kathy; Thai, Thuan; Thomas, Shane R; Göttgens, Berthold; Lacaud, Georges; Kouskoff, Valerie et al. (Company of Biologists, 2015-05-15)
      During embryonic development, hematopoietic cells develop by a process of endothelial-to hematopoietic transition of a specialized population of endothelial cells. These hemogenic endothelium (HE) cells in turn develop ...
    • Endolysosomes are the principal intracellular sites of acid hydrolase activity 

      Bright, Nicholas Alexander; Davis, Luther J; Luzio, John Paul (Elsevier (Cell Press), 2016-08-04)
      The endocytic delivery of macromolecules from the mammalian cell surface for degradation by lysosomal acid hydrolases requires traffic through early endosomes to late endosomes, followed by transient (kissing) or complete ...
    • Endometrial glands as a source of nutrients, growth factors and cytokines during the first trimester of human pregnancy: A morphological and immunohistochemical study 

      Hempstock, Joanne; Cindrova-Davies, Tereza; Jauniaux, Eric; Burton, Graham James (2004-07-20)
      Abstract Background The maternal circulation to the human placenta is not fully established until 10–12 weeks of pregnancy. During the first trimester the intervillous space is filled by a clear fluid, in part derived ...
    • The endoplasmic reticulum remains functionally connected by vesicular transport after its fragmentation in cells expressing Z-$\textit{α}$$_{1}$-antitrypsin 

      Dickens, Jennifer Amy; Ordóñez, Adriana; Chambers, Joseph E; Beckett, Alison J; Patel, Vruti; Malzer, Elke; Dominicus, Caia S et al. (Federation of American Societies for Experimental Biology, 2016-09-06)
      $\textit{α}$$_{1}$-Antitrypsin is a serine protease inhibitor produced in the liver that is responsible for the regulation of pulmonary inflammation. The commonest pathogenic gene mutation yields Z-$\textit{α}$$_{1}$-antitrypsin, ...
    • Endoplasmic reticulum stress in lung disease. 

      Marciniak, Stefan John (2017-06-28)
    • Endoplasmic reticulum stress is induced in the human placenta during labour 

      Veerbeek, JHW; Tissot, Van Patot MC; Burton, Graham James; Yung, Hong Wa (Elsevier, 2014-11-15)
      Placental endoplasmic reticulum (ER) stress has been postulated in the pathophysiology of pre-eclampsia (PE) and intrauterine growth restriction (IUGR), but its activation remains elusive. Oxidative stress induced by ...
    • Endosymbiosis undone by stepwise elimination of the plastid in a parasitic dinoflagellate 

      Gornik, Sebastian G; Febrimarsa,,; Cassin, Andrew M; MacRae, James I; Ramaprasad, Abhinay; Rchiad, Zineb; McConville, Malcolm J et al. (National Academy of Sciences, 2015-04-20)
      Organelle gain through endosymbiosis has been integral to the origin and diversification of eukaryotes, and, once gained, plastids and mitochondria seem seldom lost. Indeed, discovery of nonphotosynthetic plastids in many ...