Now showing items 2241-2260 of 215388

    • Association of breast cancer risk with genetic variants showing differential allelic expression: Identification of a novel breast cancer susceptibility locus at 4q21 

      Hamdi, Y; Soucy, P; Adoue, V; Michailidou, K; Canisius, S; Lemaçon, A; Droit, A et al. (Impact Journals, 2016-10-21)
      There are significant inter-individual differences in the levels of gene expression. Through modulation of gene expression, $\textit{cis}$-acting variants represent an important source of phenotypic variation. Consequently, ...
    • Association of British Neurologists: revised (2015) guidelines for prescribing disease-modifying treatments in multiple sclerosis. 

      Scolding, N; Barnes, D; Cader, S; Chataway, J; Chaudhuri, A; Coles, A; Giovannoni, G et al. (BMJ Publishing Group, 2015-08-01)
    • An Association of Cancer Physicians’ strategy for improving services and outcomes for cancer patients 

      Baird, Richard; Banks, Ian; Cameron, David; Chester, John; Earl, Helena; Flannagan, Mark; Januszewski, Adam et al. (Cancer Intelligence, 2016-01-05)
      The Association of Cancer Physicians in the United Kingdom has developed a strategy to improve outcomes for cancer patients and identified the goals and commitments of the Association and its members.
    • The association of coffee intake with liver cancer risk is mediated by biomarkers of inflammation and hepatocellular injury: data from the European Prospective Investigation into Cancer and Nutrition 

      Aleksandrova, Krasimira; Bamia, Christina; Drogan, Dagmar; Lagiou, Pagona; Trichopoulou, Antonia; Jenab, Mazda; Fedirko, Veronika et al. (American Society for Nutrition, 2015-11-11)
      BACKGROUND: Higher coffee intake has been purportedly related to a lower risk of liver cancer. However, it remains unclear whether this association may be accounted for by specific biological mechanisms. ...
    • Association of cognition with functional trajectories in patients admitted to geriatric wards: A retrospective observational study 

      Hartley, Peter; Alexander, Kerry; Adamson, Jennifer; Cunningham, Carol; Georgina, Embleton; Romero-Ortuno, Roman (Wiley, 2016-09-16)
      Aim Impaired cognition is common among older patients admitted to acute hospitals, but its association with functional trajectories has not been well studied. Methods A retrospective observational study was carried ...
    • Association of common variation in the PPARAgene with incident myocardial infarction in individuals with type 2 diabetes: A Go-DARTS study 

      Doney, Alex S. F.; Fischer, Bettina; Lee, Simon; Morris, Andrew D.; Leese, Graham P.; Palmer, Colin N. A. (2005-11-25)
      Background Common variants of the PPARA gene have been found to associate with ischaemic heart disease in non diabetic men. The L162V variant was found to be protective while the C2528G variant increased risk. L162V has ...
    • Association of comorbidity and health service usage among patients with dementia in the UK: a population-based study 

      Browne, J; Edwards, DA; Rhodes, KM; Brimicombe, DJ; Payne, RA (BMJ Publishing Group, 2017-03-01)
      $\textbf{BACKGROUND}$: The majority of people with dementia have other long-term diseases, the presence of which may affect the progression and management of dementia. This study aimed to identify subgroups with higher ...
    • Association of Descriptors of Breathlessness With Diagnosis and Self-Reported Severity of Breathlessness in Patients With Advanced Chronic Obstructive Pulmonary Disease or Cancer 

      Chowienczyk, Sarah; Javadzadeh, Shagayegh; Booth, Sara; Farquhar, Morag (Elsevier, 2016-05-24)
      $\textbf{Context}$ Verbal descriptors are important in understanding patients' experience of breathlessness. $\textbf{Objectives}$ The aim of this study was to examine the association between selection of ...
    • Association of Dietary, Circulating, and Supplement Fatty Acids With Coronary Risk: A Systematic Review and Meta-analysis 

      Chowdhury, Rajiv; Warnakula, Samantha; Kunutsor, Setor; Crowe, Francesca; Ward, Heather A.; Johnson, Laura; Franco, Oscar H. et al. (American College of Physicians, 2014-03-18)
      Background: Guidelines advocate changes in fatty acid consumption to promote cardiovascular health. Purpose: To summarize evidence about associations between fatty acids and coronary disease. Data Sources: MEDLINE, ...
    • Association of faecal elastase 1 with non-fasting triglycerides in type 2 diabetes 

      Rathmann, Wolfgang; Haastert, Burkhard; Oscarsson, Jan; Berglind, Niklas; Lindkvistd, Björn; Wareham, Nicholas J. (Elsevier, 2016-03-30)
      Aims: Intestinal absorption of esterified fatty acids depends on exocrine pancreatic function and influences plasma triglycerides levels. The aim was to investigate the association of reduced exocrine pancreatic function ...
    • Association of genetic susceptibility variants for type 2 diabetes with breast cancer risk in women of European ancestry 

      Zhao, Zhiguo; Wen, Wanqing; Michailidou, Kyriaki; Bolla, Manjeet K.; Wang, Qin; Zhang, Ben; Long, Jirong et al. (Springer, 2016-04-06)
      Purpose Type 2 diabetes (T2D) has been reported to be associated with an elevated risk of breast cancer. It is unclear, however, whether this association is due to shared genetic factors. Methods We constructed a ...
    • The association of geriatric syndromes with hospital outcomes 

      Romero Ortuno, Roman; Forsyth, Duncan R.; Wilson, Jane; Cameron, Ewen; Wallis, Stephen; Biram, Richard; Keevil, Victoria (Wiley, 2016-02-01)
      Background Frailty, history of dementia (HoD), and acute confusional states (ACS) are common in older patients admitted to hospital. Objective To study the association of frailty (≥6 points in the Clinical Frailty ...
    • Association of hypertension and hyperglycaemia with socioeconomic contexts in resource-poor settings: the Bangladesh Demographic and Health Survey 

      Harshfield, E; Chowdhury, R; Harhay, MN; Bergquist, H; Harhay, MO (Oxford University Press, 2015-10)
      BACKGROUND: Cardiovascular diseases and risk factors are disproportionally concentrated among the socioeconomically disadvantaged in high-income countries; however, this relationship is not well-understood or documented ...
    • Association of MTHFR C677T Genotype With Ischemic Stroke Is Confined to Cerebral Small Vessel Disease Subtype 

      Rutten-Jacobs, Loes C. A.; Traylor, Matthew; Adib-Samii, Poneh; Thijs, Vincent; Sudlow, Cathie; Rothwell, Peter M.; Boncoraglio, Giorgio et al. (American Heart Association, 2016-02-02)
      Background and Purpose—Elevated plasma homocysteine levels are associated with stroke. However, this might be a reflection of bias or confounding because trials have failed to demonstrate an effect from homocysteine lowering ...
    • The Association of Multiple Biomarkers of Iron Metabolism and Type 2 Diabetes - the EPIC-InterAct Study 

      Podmore, Clara; Meidtner, Karina; Schulze, Matthias B.; Scott, Robert A.; Ramond, Anna; Butterworth, Adam S.; di Angelantonio, Emanuele et al. (American Diabetes Association, 2016-02-09)
      Objective: Observational studies show an association between ferritin and type 2 diabetes (T2D), suggesting a role of high iron stores for T2D development. However, ferritin is influenced by factors other than iron stores, ...
    • Association of plasma phospholipid n-3 and n-6 polyunsaturated fatty acids with type 2 diabetes: The EPIC-InterAct case-cohort study 

      Forouhi, Nita G.; Imamura, Fumiaki; Sharp, Stephen J.; Koulman, Albert; Schulze, Matthias B.; Zheng, Jusheng; Ye, Zheng et al. (Public Library of Science, 2016-07-19)
      ${\bf Background:}$ Whether and how n-3 and n-6 polyunsaturated fatty acids (PUFAs) are related to type 2 diabetes (T2D) is debated. Objectively measured plasma PUFAs can help to clarify these associations. ${\bf ...
    • Association of self-rated health with multimorbidity, chronic disease and psychosocial factors in a large middle-aged and older cohort from general practice: a cross-sectional study 

      Mavaddat, Nahal; Valderas, Jose M.; van der Linde, Rianne; Khaw, Kay-Tee; Kinmonth, Ann Louise (BioMed Central, 2014-11-25)
      Background: The prevalence of coexisting chronic conditions (multimorbidity) is rising. Disease labels, however, give little information about impact on subjective health and personal illness experience. We aim to examine ...
    • Association of the Clinical Frailty Scale (CFS) with hospital outcomes 

      Wallis, S. J.; Wall, J.; Biram, R. W. S.; Romero-Ortuno, R. (OUP, 2015-03-16)
      Background: the clinical frailty scale (CFS) was validated as a predictor of adverse outcomes in community-dwelling older people. In our hospital, the use of the CFS in emergency admissions of people aged ≥ 75 years was ...
    • Association of the Cold Shock DEAD-Box RNA Helicase RhlE to the RNA Degradosome in $\textit{Caulobacter crescentus}$ 

      Aguirre, AA; Vicente, AM; Hardwick, SW; Alvelos, DM; Mazzon, RR; Luisi, BF; Marques, MV (American Society for Microbiology, 2017-07-01)
      In diverse bacterial lineages, multienzyme assemblies have evolved that are central elements of RNA metabolism and RNA-mediated regulation. The aquatic Gram-negative bacterium $\textit{Caulobacter crescentus}$, which has ...