Now showing items 1956-1975 of 9320

    • Design and delivery of a national pilot survey of capabilities 

      Tenneti, Raji; Goodman-Deane, Joy; Langdon, Patrick; Waller, Sam; Ruggeri, Kai; Clarkson, P. John; Huppert, Felicia A. (Inderscience Publishers, 2014-02-19)
      Understanding the numbers of people with different levels of ability in the population is important for informing design decisions for mainstream products, but a survey dataset for this purpose does not exist. This paper ...
    • Design and Modelling of Solidly-Mounted Resonators for Low-Cost Particle Sensing 

      Villa-López, Farah Helue; Rughoobur, Girish; Thomas, Sanju; Flewitt, Andrew J.; Cole, Marina; Gardner, Julian W. (IOP Science, 2015-12-18)
      This work presents the design and fabrication of Solidly Mounted Resonator (SMR) devices for the detection of particulate matter (PM2.5 and PM10) in order to develop a smart low-cost particle sensor for air quality. These ...
    • Design and validation of a near-infrared fluorescence endoscope for detection of early esophageal malignancy using a targeted imaging probe 

      Waterhouse, Dale J.; Joseph, James; Neves, Andre A.; di Pietro, Massimiliano; Brindle, Kevin M.; Fitzgerald, Rebecca C.; Bohndiek, Sarah E. (SPIE, 2016-08-04)
      Barrett’s esophagus is a known precursor lesion to esophageal adenocarcinoma. In these patients, early detection of premalignant disease, known as dysplasia, allows curative minimally invasive endoscopic therapy, but is ...
    • Design Considerations for the Brushless Doubly-Fed (Induction) Machine 

      McMahon, R. A.; Mathekga, M. E.; Wang, X.; Tatlow, M. R. (IET, 2015)
      A design procedure for the Brushless Doubly Fed machine is based on equations derived from a simplified equivalent circuit. The method allows the many variables in the design of this machine to be handled in straightforward ...
    • Design of a low-cost and compact 1 × 5 wavelength-selective switch for access networks 

      Lu, Tianxin; Collings, Neil; Robertson, Brian; Chu, Daping (The Optical Society, 2015-09-16)
      This paper describes the design, modeling, construction, and testing of a low-cost and compact (80  mm×50  mm) 1×5 wavelength-selective switch. The core beam-deflecting element of the switch is a nematic liquid crystal on ...
    • Design of Highly Selective Platinum Nanoparticle Catalysts for the Aerobic Oxidation of KA-Oil using Continuous-Flow Chemistry 

      Gill, Arran M.; Hinde, Christopher S.; Leary, Rowan K.; Potter, Matthew E.; Jouve, Andrea; Wells, Peter P.; Midgley, Paul A. et al. (Wiley, 2016-02-02)
      Highly active and selective aerobic oxidation of KA-oil to cyclo-hexanone(precursor for adipic acid and e-caprolactam) has been achieved in high yields using continuous-flow chemistry by utilizing uncapped noble-metal(Au, ...
    • Design of passive vehicle suspensions for maximal least damping ratio 

      Smith, Malcolm C.; Swift, Stuart J. (Taylor & Francis., 2016)
      This paper studies the use of the least damping ratio among system poles as a performance metric in passive vehicle suspensions. Methods are developed which allow optimal solutions to be computed in terms of non-dimensional ...
    • Design of Positive-Definite Quaternion Kernels 

      Tobar, Felipe; Mandic, Danilo P. (IEEE, 2015-07-16)
      Quaternion reproducing kernel Hilbert spaces (QRKHS) have been proposed recently and provide a highdimensional feature space (alternative to the real-valued multikernel approach) for general kernel-learning applications. ...
    • A design protocol for tailoring ice-templated scaffold structure 

      Pawelec, K. A.; Husmann, A.; Best, Serena Michelle; Cameron, Ruth Elizabeth (Royal Society Publishing, 2014-03-06)
      In this paper, we show, for the first time, the key link between scaffold architecture and latent heat evolution during the production of porous biomedical collagen structures using freeze-drying. Collagen scaffolds are ...
    • Design Study for a Laminar-Flying-Wing Aircraft 

      Saeed, T. I.; Graham, W. R. (American Institute of Aeronautics and Astronautics, 2015-05-20)
      The Greener by Design initiative has identified the laminar-flying-wing configuration as the most promising long-term prospect for fuel-efficient civil aviation. However, in the absence of detailed evaluations, its potential ...
    • Design thinking to enhance the sustainable business modelling process - A workshop based on a value mapping process 

      Geissdoerfer, Martin; Bocken, Nancy M. P.; Hultink, Erik Jan (Elsevier, 2016-07-07)
      Sustainable business model innovation is an emerging topic, but only few tools are currently available to assist companies in sustainable business modelling. This paper works towards closing this gap by bringing together ...
    • Design with uncertainty: the role of future options for infrastructure integration 

      Martani, Claudio; Jin, Ying; Soga, Kenichi; Scholtes, Stefan (Wiley, 2016)
      Decision-making for effective infrastructure integration is challenging because the performance of long-lasting facilities is often difficult to foresee or well beyond the designer’s control. We propose a new approach for ...
    • Design, Characterization, and First-In-Human Study of the Vascular Actions of a Novel Biased Apelin Receptor Agonist 

      Brame, Aimee L.; Maguire, Janet J.; Yang, Peiran; Dyson, Alex; Torella, Rubben; Cheriyan, Joseph; Singer, Mervyn et al. (American Heart Association, 2015-02-23)
      [Pyr1]apelin-13 is an endogenous vasodilator and inotrope but is downregulated in pulmonary hypertension and heart failure, making the apelin receptor an attractive therapeutic target. Agonists acting at the same ...
    • The design, synthesis and evaluation of tetra-substituted pyr-idines as potent 5-HT2C receptor agonists 

      Rouquet, Guy; Moore, Dianna E.; Spain, Malcolm; Allwood, Daniel M.; Battilocchio, Claudio; Blakemore, David C.; Fish, Paul V. et al. (American Chemical Society, 2015-01-20)
      A series of pyrido[3,4-d]azepines that are potent and selective 5-HT2C receptor agonists is disclosed. Compound 7 (PF-04781340) is identified as a suitable lead owing to good 5-HT2C potency, selectivity over 5-HT2B agonism ...
    • Designer Requirements for Visual Capability Loss Simulator Tools: Differences between Design Disciplines 

      Cornish, Katie; Goodman-Deane, Joy; Clarkson, P. John (Springer, 2014)
      There is a low uptake of inclusive design tools in industry, partly due to a poor fit between design tools and the thought and work processes of designers. Simulating visual capability losses is a technique with great ...
    • Designing a 'concept of operations' architecture for next generation multi-organisational service networks 

      Harrington, Tomás Seosamh; Srai, Jagjit Singh (Springer, 2016)
      Networked service organisations are increasingly adopting a 'smarter networking' philosophy in their design of more agile and customer-focused supply models. Changing consumer behaviours and the emergence of transformative ...
    • Designing a More Inclusive World 

      Waller, Sam; Langdon, Pat; Clarkson, John (Emerald Group Publishing, 2010)
      This paper summarises the what, why and how of inclusive design, and presents key contributions of the 2006–2010 i~design research consortium, the third successive research consortium funded by the Engineering and Physical ...
    • Designing a more nonlinearly stable laminar flow via boundary manipulation 

      Rabin, S. M. E.; Caulfield, C. P.; Kerswell, R. R. (Cambridge University Press, 2013-12-04)
      We show how a fully nonlinear variational method can be used to design a more nonlinearly stable laminar shear flow by quantifying the effect of manipulating the boundary conditions of the flow. Using the example of plane ...
    • Designing and Undertaking a Health Economics Study of Digital Health Interventions 

      McNamee, Paul; Murray, Elizabeth; Kelly, Michael P.; Bojke, Laura; Chilcott, Jim; Fischer, Alastair; West, Robert et al. (Elsevier, 2016)
      This paper introduces and discusses key issues in the economic evaluation of digital health interventions. The purpose is to stimulate debate so that existing economic techniques may be refined or new methods developed. ...
    • Designing change: coins and the creation of new national identities 

      Eagleton, Catherine (Manchester University Press, 2016-01-01)
      Designs on currency are often seen as markers of political change, with the change in images at independence seen as a visual representation of the new nation. However, most studies have looked only at one country, and ...