Now showing items 2527-2546 of 18169

    • Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease 

      Stitziel, Nathan O; Stirrups, Kathleen Elizabeth; Masca, Nicholas GD; Erdmann, Jeanette; Ferrario, Paola G; König, Inke R; Weeke, Peter E et al. (Massachusetts Medical Society, 2016-03-02)
      BACKGROUND The discovery of low-frequency coding variants affecting the risk of coronary artery disease has facilitated the identification of therapeutic targets. METHODS Through DNA genotyping, we tested 54,003 ...
    • Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease (vol 374, pg 1134, 2016) 

      Stitziel, Nathan O; Stirrups, Kathleen Elizabeth; Masca, Nicholas GD; Erdmann, Jeanette; Ferrario, Paola G; Koenig, Inke R; Weeke, Peter E et al. (2016-05-12)
    • Coding/decoding two-dimensional images with orbital angular momentum of light 

      Chu, Jiaqi; Li, Xuefeng; Smithwick, Quinn; Chu, Daping (The Optical Society, 2016-03-23)
      We investigate encoding and decoding of two-dimensional information using the orbital angular momentum (OAM) of light. Spiral phase plates and phase-only spatial light modulators are used in encoding and decoding of OAM ...
    • Codon-Driven Translational Efficiency Is Stable across Diverse Mammalian Cell States 

      Rudolph, Konrad Ludwig; Schmitt, Bianca M; Villar, Diego; White, Robert J; Marioni, John Carlo; Kutter, Claudia; Odom, Duncan (PLOS, 2016-05-11)
      Whether codon usage fine-tunes mRNA translation in mammals remains controversial, with recent papers suggesting that production of proteins in specific Gene Ontological (GO) pathways can be regulated by actively modifying ...
    • Coenzyme Q10 prevents hepatic fibrosis, inflammation, and oxidative stress in a male rat model of poor maternal nutrition and accelerated postnatal growth 

      Tarry-Adkins, Jane L; Fernandez-Twinn, Denise Sylvia; Hargreaves, Iain P; Neergheen, Viruna; Aiken, Catherine Elizabeth; Martin-Gronert, Malgorzata; McConnell, Josie M et al. (American Society for Nutrition, 2015-12-30)
      BACKGROUND: It is well-established that low birth-weight and accelerated postnatal growth increases risk of liver dysfunction in later life. However, molecular mechanisms underlying such developmental programming are not ...
    • Coenzyme Q10 prevents insulin signaling dysregulation and inflammation prior to development of insulin resistance in male offspring of a rat model of poor maternal nutrition and accelerated postnatal growth 

      Tarry-Adkins, Jane; Fernandez-Twinn, Denise Sylvia; Madsen, Ralitsa; Chen, Jian-Hua; Carpenter, Asha; Hargreaves, Iain; McConnell, Josie et al. (Endocrine Society, 2015-07-27)
      Low birth-weight and rapid postnatal-growth increases the risk of developing insulin resistance and type-2 diabetes in later life. However underlying mechanisms and potential intervention strategies are poorly defined. ...
    • The coevolution of play and the cortico-cerebellar system in primates 

      Kerney, Max; Smaers, Jeroen B.; Schoenemann, P. Thomas; Dunn, Jacob Charles (2017-10)
    • Coevolution of RAC Small GTPases and their Regulators GEF Proteins 

      Jiménez-Sánchez, Alejandro (Libertas Academica, 2016-05-17)
      RAC proteins are small GTPases involved in important cellular processes in eukaryotes, and their deregulation may contribute to cancer. Activation of RAC proteins is regulated by DOCK and DBL protein families of guanine ...
    • Coffee Drinking and Mortality in 10 European Countries: A Multinational Cohort Study 

      Gunter, Marc J; Murphy, Neil; Cross, Amanda J; Dossus, Laure; Dartois, Laureen; Fagherazzi, Guy; Kaaks, Rudolf et al. (American College of Physicians, 2017-08-15)
      Background: The relationship between coffee consumption and mortality in diverse European populations with variable coffee preparation methods is unclear. Objective: To examine whether coffee consumption is associated with ...
    • Coffee, tea and melanoma risk: findings from the European Prospective Investigation into Cancer and Nutrition 

      Caini, S; Masala, G; Saieva, C; Kvaskoff, M; Savoye, I; Sacerdote, C; Hemmingsson, O et al. (John Wiley & Sons Inc., 2017-02-20)
      In vitro and animal studies suggest that bioactive constituents of coffee and tea may have anticarcinogenic effects against cutaneous melanoma, however epidemiological evidence is limited to date. We examined the relationships ...
    • Cognition as a treatment target in depression 

      Kaser, Muzaffer; Zaman, R; Sahakian, Barbara Jacquelyn (Cambridge University Press, 2017-04-01)
      Cognitive dysfunction in depression is associated with poorer clinical outcomes and impaired psychosocial functioning. However, most treatments for depression do not specifically target cognition. Neurocognitive deficits ...
    • Cognition in people with Prader-Willi syndrome: Insights into genetic influences on cognitive and social development 

      Whittington, Joyce Enid; Holland, Anthony John (Elsevier, 2016-11-09)
      We present a mini-review of cognition in Prader-Willi syndrome. Studies cited include findings on general ability (IQ), IQ correlates with family members, strengths and weaknesses in cognitive profiles in genetic subtypes, ...
    • The Cognitive and Behavioural Impact of Alcohol Promoting and Alcohol Warning Advertisements: An Experimental Study 

      Brown, Kyle G; Stautz, Kai-Denis; Hollands, Gareth John; Winpenny, Eleanor Margaret; Marteau, Theresa (Oxford University Press, 2015-09-20)
      Aims: To assess the immediate effect of alcohol promoting and alcohol warning advertisements on implicit and explicit attitudes towards alcohol and on alcohol seeking behaviour. Methods: We conducted a between-participants ...
    • Cognitive and behavioural predictors of quit attempts and biochemically-validated abstinence during pregnancy 

      Emery, Joanne Louise; Sutton, Stephen Robert; Naughton, Felix (Oxford University Press, 2016)
      $\textbf{Introduction}$: Initiating a quit attempt and achieving abstinence are distinct behaviours that have distinct correlates in general smokers. Studies predicting prenatal smoking have not addressed this. ...
    • Cognitive and Emotional Math Problems Largely Dissociate: Prevalence of Developmental Dyscalculia and Mathematics Anxiety 

      Devine, A; Hill, F; Carey, E; Szucs, Denes (2017-10-26)
      © 2017 APA, all rights reserved). A negative correlation between math anxiety and mathematics performance is frequently reported. Thus, some may assume that high levels of mathematics anxiety are associated with poor ...
    • Cognitive Behavioral Therapy Lowers Elevated Functional Connectivity in Depressed Adolescents 

      Chattopadhyay, Shayanti; Tait, R; Simas, T; van Nieuwenhuizen, A; Hagan, CC; Holt, Rosemary Jane; Graham, J et al. (Elsevier, 2017-03-01)
      Imaging studies have implicated altered functional connectivity in adults with major depressive disorder (MDD). Whether similar dysfunction is present in adolescent patients is unclear. The degree of resting-state functional ...
    • Cognitive behavioural therapy and short-term psychoanalytical psychotherapy versus a brief psychosocial intervention in adolescents with unipolar major depressive disorder (IMPACT): a multicentre, pragmatic, observer-blind, randomised controlled superiority trial. 

      Goodyer, Ian Michael; Reynolds, Shirley; Barrett, Barbara; Byford, Sarah; Dubicka, Bernadka; Hill, Jonathan; Holland, Fiona et al. (Elsevier, 2017-02)
      $\textbf{BACKGROUND}$: Psychological treatments for adolescents with unipolar major depressive disorder are associated with diagnostic remission within 28 weeks in 65-70% of patients. We aimed to assess the medium-term ...
    • Cognitive biases in binge eating disorder: the hijacking of decision making 

      Voon, Valerie (Cambridge University Press, 2015-11-23)
      Binge eating disorder (BED) is the most common of eating disorders and is characterized by excessive out of control rapid food intake. This review focuses on cognitive impairments in BED which represent an endophenotype ...
    • Cognitive decline and quality of life in incident Parkinson's disease: The role of attention. 

      Lawson, Rachael A; Yarnall, Alison J; Duncan, Gordon W; Breen, David P; Khoo, Tien K; Williams-Gray, Caroline Helen; Barker, Roger Alistair et al. (2016-06)