Now showing items 2567-2586 of 12407

• #### Depletion of the RNA-binding protein RBP33 results in increased expression of silenced RNA polymerase II transcripts in Trypanosoma brucei ﻿

(PLOS, 2014-09-12)
We have characterized the RNA-binding protein RBP33 in Trypanosoma brucei, and found that it localizes to the nucleus and is essential for viability. The subset of RNAs bound to RBP33 was determined by immunoprecipitation ...
• #### Depressed mantle discontinuities beneath Iceland: Evidence of a garnet controlled 660 km discontinuity? ﻿

(Elsevier, 2015-11-09)
The presence of a mantle plume beneath Iceland has long been hypothesised to explain its high volumes of crustal volcanism. Practical constraints in seismic tomography mean that thin, slow velocity anomalies representative ...
• #### Depression and Sexual Orientation During Young Adulthood: Diversity Among Sexual Minority Subgroups and the Role of Gender Nonconformity ﻿

(Springer, 2015-04-14)
Sexual minority individuals are at an elevated risk for depression compared to their heterosexual counterparts, yet less is known about how depression status varies across sexual minority subgroups (i.e., mostly heterosexuals, ...
• #### Depression following traumatic brain injury: A functional connectivity perspective ﻿

(Taylor & Francis, 2016-07-28)
Introduction: Despite the mounting evidence that depression is one of the most common psychiatric sequelae in survivors of traumatic brain injury (TBI), no studies so far have attempted to provide an explanation in terms ...
• #### Deregulation of hydroxybutyric acid metabolism provides diagnostic and prognostic biomarkers in ovarian high-grade serous carcinomas ﻿

(American Association for Cancer Research, 2016)
Ovarian cancer is a heterogeneous disease of low prevalence but poor survival. Early diagnosis is critical for patients’ survival but often challenging because ovarian cancer symptoms are unclear and appear only in advanced ...
• #### Deregulation of Osmotic Regulation Machinery Explains and Predicts Cellular Transformation in Cancer and Disease ﻿

(Springer, 2016-09-06)
• #### The derivative discontinuity of the exchange–correlation functional ﻿

(Royal Society of Chemistry, 2014-06-02)
The derivative discontinuity is a key concept in electronic structure theory in general and density functional theory in particular. The electronic energy of a quantum system exhibits derivative discontinuities with respect ...
• #### Derivative of the standard $p$-adic $L$-function associated with a Siegel form ﻿

In this paper we construct a two variables p-adic L-function for the standard representation associated with a Hida family of parallel weight genus g Siegel forms, using a method previously developed by B\"ocherer--Schmidt ...
• #### DermO; an ontology for the description of dermatologic disease ﻿

(BioMed Central, 2016-06-13)
${\bf Background:}$ There have been repeated initiatives to produce standard nosologies and terminologies for cutaneous disease, some dedicated to the domain and some part of bigger terminologies such as ICD-10. Recently, ...
• #### The Descent of Culture ﻿

(OUP, 2014)
• #### Describing complex design practices with a cross-domain framework: Learning from Synthetic Biology and Swarm Robotics ﻿

(Springer, 2016-03-02)
This paper reports on the development of a cross-domain framework for describing complex design practices. The framework is grounded in studies of two different complex design fields: Synthetic Biology and Swarm Robotics. ...
• #### A description of interventions promoting healthier ready-to-eat meals (to eat in, to take away, or to be delivered) sold by specific food outlets in England: a systematic mapping and evidence synthesis ﻿

(BioMed Central, 2017-01-19)
$\textbf{Background:}$ Ready-to-eat meals (to eat in, to take away or to be delivered) sold by food outlets are often more energy dense and nutrient poor compared with meals prepared at home, making them a reasonable target ...
• #### The descriptive epidemiology of accelerometer-measured physical activity in older adults ﻿

(BioMed Central, 2016-01-07)
Background: Objectively measured physical activity between older individuals and between populations has been poorly described. We aimed to describe and compare the variation in accelerometry data in older UK (EPIC-Norfolk) ...
• #### Design and data modelling of fibre optic systems to monitor reinforced concrete structural elements ﻿

(ASCE, 2015)
Structural monitoring of built assets, performed to ensure safety, usability, and to better understand the assets’ structural behaviour, is becoming common practice. One method to monitor structural behaviour is to use ...
• #### Design and delivery of a national pilot survey of capabilities ﻿

(Inderscience Publishers, 2014-02-19)
Understanding the numbers of people with different levels of ability in the population is important for informing design decisions for mainstream products, but a survey dataset for this purpose does not exist. This paper ...
• #### Design and implementation of a low-power hybrid capacitive MEMS oscillator ﻿

(Elsevier, 2016-10-01)
This paper reports on the design and implementation of a low power MEMS oscillator based on capacitively transduced silicon micromachined resonators. The analysis shows how design parameters of MEMS resonator impact on the ...
• #### Design and Modelling of Solidly-Mounted Resonators for Low-Cost Particle Sensing ﻿

(IOP Science, 2015-12-18)
This work presents the design and fabrication of Solidly Mounted Resonator (SMR) devices for the detection of particulate matter (PM2.5 and PM10) in order to develop a smart low-cost particle sensor for air quality. These ...
• #### Design and validation of a near-infrared fluorescence endoscope for detection of early esophageal malignancy using a targeted imaging probe ﻿

(SPIE, 2016-08-04)
Barrett’s esophagus is a known precursor lesion to esophageal adenocarcinoma. In these patients, early detection of premalignant disease, known as dysplasia, allows curative minimally invasive endoscopic therapy, but is ...
• #### A design concept of parallel elasticity extracted from biological muscles for engineered actuators. ﻿

(IOP Publishing, 2016-08-23)
Series elastic actuation that takes inspiration from biological muscle-tendon units has been extensively studied and used to address the challenges (e.g. energy efficiency, robustness) existing in purely stiff robots. ...
• #### Design Considerations for the Brushless Doubly-Fed (Induction) Machine ﻿

(IET, 2016-06-04)
A design procedure for the Brushless Doubly Fed machine is based on equations derived from a simplified equivalent circuit. The method allows the many variables in the design of this machine to be handled in straightforward ...