Now showing items 2865-2884 of 14289

    • DeepEar: Robust Smartphone Audio Sensing in Unconstrained Acoustic Environments using Deep Learning 

      Lane, Nicholas D.; Georgiev, Petko; Qendro, Lorena (ACM, 2015-09)
      Microphones are remarkably powerful sensors of human behavior and context. However, audio sensing is highly susceptible to wild fluctuations in accuracy when used in diverse acoustic environments (such as, bedrooms, vehicles, ...
    • Deeply buried glacigenic-debris flows imaged in 3D-seismic data from the early Quaternary sediments of the northern North Sea 

      Ottesen, D.; Dowdeswell, J. A.; Bugge, T. (Geological Society of London, 2016)
      Debris flows composed of diamictic glacial sediment are found on the continental slope offshore of many former ice streams in the Arctic and Antarctic (Vorren et al. 1998). The debris flows are often stacked, making up ...
    • Default mode dynamics for global functional integration 

      Vatansever, Deniz; Menon, David; Manktelow, Anne; Sahakian, Barbara; Stamatakis, Emmanuel (Society for Neuroscience, 2015-11-18)
      The default mode network (DMN) has been traditionally assumed to hinder behavioral performance in externally focused, goal-directed paradigms and to provide no active contribution to human cognition. However, recent evidence ...
    • Default mode hypoconnectivity underlies a sex-related autism spectrum 

      Ypma, Rolf J. F.; Moseley, Rachel L.; Holt, Rosemary J.; Rughooputh, Naresh; Floris, Dorothea L.; Chura, Lindsay R.; Spencer, Michael D. et al. (Elsevier, 2016)
      Background: Females and males differ significantly in the prevalence and presentation of autism spectrum conditions. One theory of this effect postulates that autistic traits lie on a sex-related continuum in the general ...
    • Default mode network connectivity during task execution 

      Vatansever, D.; Menon, D. K.; Manktelow, A. E.; Sahakian, B. J.; Stamatakis, E. A. (Elsevier, 2015-07-26)
      Initially described as task-induced deactivations during goal-directed paradigms of high attentional load, the unresolved functionality of default mode regions has long been assumed to interfere with task performance. ...
    • The Default Mode Network is Disrupted in Parkinson's Disease with Visual Hallucinations 

      Yao, Nailin; Chang, Richard Shek-Kwan; Cheung, Charlton; Pang, Shirley; Lau, Kui Kai; Suckling, John; Rowe, James B. et al. (Wiley, 2014-07-01)
      Background: Visual hallucinations (VH) are one of the most striking nonmotor symptoms in Parkinson's disease (PD), and predict dementia and mortality. Aberrant default mode network (DMN) is associated with other psychoses. ...
    • Defect Formation beyond Kibble-Zurek Mechanism and Holography 

      Chesler, Paul M.; García-García, Antonio M.; Liu, Hong (APS, 2015-05-14)
      We study the dynamic after a smooth quench across a continuous transition from the disordered phase to the ordered phase. Based on scaling ideas, linear response, and the spectrum of unstable modes, we develop a theoretical ...
    • Defect state passivation at III-V oxide interfaces for complementary metal-oxide-semiconductor devices 

      Robertson, J.; Guo, Y.; Lin, L. (AIP Publishing, 2014)
      The paper describes the reasons for the greater difficulty in the passivation of interface defects of III-V semiconductors like GaAs. These include the more complex reconstructions of the starting surface which already ...
    • Defective ATG16L1-mediated removal of IRE1α drives Crohn's disease-like ileitis. 

      Tschurtschenthaler, M; Adolph, TE; Ashcroft, JW; Niederreiter, L; Bharti, R; Saveljeva, S; Bhattacharyya, J et al. (Rockefeller University Press, 2017-02-01)
      ATG16L1$^{T300A}$, a major risk polymorphism in Crohn's disease (CD), causes impaired autophagy, but it has remained unclear how this predisposes to CD. In this study, we report that mice with Atg16l1 deletion in intestinal ...
    • Defective erythropoiesis in a mouse model of reduced Fbxo7 expression due to decreased p27 expression 

      Randle, Suzanne J.; Nelson, David E.; Patel, Shachi; Laman, Heike (Wiley, 2015-06-23)
      During the final stages of erythropoiesis, lineage-restricted progenitors mature over three to five cell divisions culminating with withdrawal from the cell cycle and the loss of most organelles, including mitochondria ...
    • Defective leukocyte adhesion and chemotaxis contributes to combined immunodeficiency in humans with autosomal recessive MST1 deficiency 

      Dang, Tarana Singh; Willet, Joseph D. P.; Griffin, Helen R.; Morgan, Neil V.; O'Boyle, Graeme; Arkwright, Peter D.; Hughes, Stephen M. et al. (Springer, 2016-01-22)
      Purpose To investigate the clinical and functional aspects of MST1 (STK4) deficiency in a profoundly CD4-lymphopenic kindred with a novel homozygous nonsense mutation in STK4. Although recent studies have described the ...
    • Defective PITRM1 mitochondrial peptidase is associated with Aβ amyloidotic neurodegeneration 

      Brunetti, D; Torsvik, J; Dallabona, C; Teixeira, P; Sztromwasser, P; Fernandez-Vizarra, E; Cerutti, R et al. (2015-01-01)
    • Defective Sphingosine-1-phosphate metabolism is a druggable target in Huntington's disease 

      Di Pardo, A; Amico, E; Basit, A; Armirotti, A; Joshi, P; Neely, DM; Vuono, R et al.
      Huntington's disease is characterized by a complex and heterogeneous pathogenic profile. Studies have shown that disturbance in lipid homeostasis may represent a critical determinant in the progression of several ...
    • Defects and disorder in metal organic frameworks 

      Cheetham, Tony; Bennett, Thomas Douglas; Coudert, François-Xavier; Goodwin, Andrew (Royal Society of Chemistry, 2015-12-21)
      Across the materials spectrum, it is widely known that the presence of both point and extended defects can have a dramatic impact on properties. Defects are however normally associated with disorder, and here we explore ...
    • Defects in ER–endosome contacts impact lysosome function in hereditary spastic paraplegia 

      Allison, R; Edgar, JR; Pearson, G; Rizo, T; Newton, T; Günther, S; Berner, F et al. (Rockefeller University Press, 2017-05-01)
      Contacts between endosomes and the endoplasmic reticulum (ER) promote endosomal tubule fission, but the mechanisms involved and consequences of tubule fission failure are incompletely understood. We found that interaction ...
    • Defects in III-Nitride Microdisk Cavities 

      Ren, C. X.; Puchtler, T. J.; Zhu, T.; Griffiths, J. T.; Oliver, R. A. (Institute of Physics, 2016)
      Nitride microcavities offer an exceptional platform for the investigation of light-matter interactions as well as the development of devices such as high efficiency light emitting diodes (LEDs) and low-threshold nanolasers. ...
    • Defects in the NC2 repressor affect both canonical and non-coding RNA polymerase II transcription initiation in yeast 

      Gómez-Navarro, Natalia; Jordán-Pla, Antonio; Estruch, Francisco; E. Pérez-Ortín, José (2016-03-03)
      Abstract Background The formation of the pre-initiation complex in eukaryotic genes is a key step in transcription initiation. The TATA-binding protein (TBP) is a universal ...
    • Defence Expenditure and Economic Growth: Evidence from India 

      Tiwari, Aviral Kumar; Tiwari, A. P. (Association of Cambridge Studies, 2010)
    • Defending China’s National Image and ‘Defensive Soft Power’: the Case of Hong Kong’s ‘Umbrella Revolution’ 

      Loh, Dylan (Springer, 2016-06-18)
      This study examines the pro-democracy protests of Hong Kong in 2014 and how the protests became sites for Beijing’s representations of Chinese national image(s). It argues that ‘defensive soft power’ can be used to understand ...
    • Defending truthmaker non-maximalism 

      Simpson, Matthew (Wiley on behalf of the Northern Institute of Philosophy, 2014-12-05)
      Jago (2012) argues that truthmaker non-maximalism, the view that some but not all truths require truthmakers, is vulnerable to a challenge from truths which ascribe knowledge of propositions about things which don't exist. ...