Now showing items 2865-2884 of 13213

• #### Development of a Cambridge Structural Database Subset: A Collection of Metal-Organic Frameworks for Past, Present, and Future ﻿

(American Chemical Society, 2017-04-11)
We report the generation and characterization of the most complete collection of metal-organic frameworks (MOFs) maintained and updated, for the first time, by the Cambridge Crystallographic Data Centre (CCDC). To set up ...
• #### Development of a facial expression scale using footrot and mastitis as models of pain in sheep. ﻿

(Elsevier, 2016-01-19)
Management of pain in sheep is limited by the challenges of recognising and accurately quantifying pain in this species. The use of facial expression scoring to assess pain is a well-utilised, practical tool in both humans ...
• #### Development of a Minimalistic Pneumatic Quadruped Robot for Fast Locomotion ﻿

(IEEE, 2012-12-14)
In this paper, we describe the development of the quadruped robot ”Ken” with the minimalistic and lightweight body design for achieving fast locomotion. We use McKibben pneumatic artificial muscles as actuators, providing ...
• #### Development of a Modelling and Simulation Method Comparison and Selection Framework for Health Services Management ﻿

(2011-05-19)
AbstractBackgroundThere is increasing recognition that modelling and simulation can assist the process of designing health care policies, strategies and operations. However, current use is limited and the questions of what ...
• #### Development of a multifunctional benzophenone linker for peptide stapling and photoaffinity labeling ﻿

(Wiley, 2016)
Photoaffinity labelling is a useful method for studying how proteins interact with ligands and biomolecules, and can help identify and characterise new targets for the development of new therapeutics. We present the design ...
• #### Development of a multiplex PCR for rapid molecular serotyping of Haemophilus parasuis ﻿

(American Society for Microbiology, 2015-09-30)
Haemophilus parasuis causes Glässer’s disease and pneumonia in pigs. Indirect haemagglutination (IHA) is used to serotype this bacterium, distinguishing fifteen serovars with some non-typeable isolates. The capsule loci ...
• #### Development of a multipurpose scaffold for the display of peptide loops ﻿

(Oxford University Press, 2017-04-24)
Protein–protein interactions (PPIs) determine a wide range of biological processes and analysis of these dynamic networks is increasingly becoming a mandatory tool for studying protein function. Using the globular ATPase ...
• #### Development of a porcine skeletal muscle cDNA microarray: analysis of differential transcript expression in phenotypically distinct muscles ﻿

(2003-03-01)
Abstract Background Microarray profiling has the potential to illuminate the molecular processes that govern the phenotypic characteristics of porcine skeletal muscles, such as hypertrophy or atrophy, and the expression ...
• #### Development of a questionnaire to assess maternal attitudes towards infant growth and milk feeding practices ﻿

(2011-04-21)
Abstract Background There is increasing recognition that public health strategies to prevent childhood obesity need to start early in life. Any behavioural interventions need to target maternal attitudes and infant feeding ...
• #### Development of a relationship between external measurements and reinforcement stress ﻿

(SPIE, 2015-03-27)
As many countries around the world face an aging infrastructure crisis, there is an increasing need to develop more accurate monitoring and assessment techniques for reinforced concrete structures. One of the challenges ...
• #### Development of a single droplet freezing apparatus for studying crystallisation in cocoa butter droplets ﻿

(Elsevier, 2014-02)
The single droplet freezing apparatus described by Pore et al. (J. Am. Oil. Chem. Soc., 86, 215-225), which allows crystallisation to be monitored in situ by X-ray diffraction, was modified to allow rapid switching of ...
• #### Development of a specific affinity-matured exosite inhibitor to MT1-MMP that efficiently inhibits tumor cell invasion in vitro and metastasis in vivo ﻿

(Impact Journals, 2016-02-27)
The membrane-associated matrix metalloproteinase-14, MT1-MMP, has been implicated in pericellular proteolysis with an important role in cellular invasion of collagenous tissues. It is substantially upregulated in various ...
• #### Development of a universal approach to increase physical activity among adolescents: The GoActive Intervention ﻿

(BMJ Publishing Group, 2015-08-25)
Objectives To develop a physical activity (PA) promotion intervention for adolescents using a process addressing gaps in the literature while considering participant engagement. We describe the initial development stages; ...
• #### Development of a universal measure of quadrupedal forelimb-hindlimb coordination using digital motion capture and computerised analysis ﻿

(2007-09-18)
Abstract Background Clinical spinal cord injury in domestic dogs provides a model population in which to test the efficacy of putative therapeutic interventions for human spinal cord injury. To achieve this potential a ...
• #### The development of a weak anion micro-capillary film for protein chromatography ﻿

(Elsevier, 2016-09-03)
In this study, the surface of a microporous walled micro-capillary film (MMCF) was modified into a weak anion exchanger by coupling cyanuric chloride and 2-diethylaminoethylamine (DEAE) to the ethylene-vinyl alcohol (EVOH) ...
• #### Development of a ‘millimanipulation’ device to study the removal of soft solid fouling layers from solid substrates and its application to cooked lard deposits ﻿

(Elsevier, 2014-10-22)
A mm-scale scraping device was developed to study the removal behaviour of soft solid fouling layers (thickness 0.5 to 10 mm) from solid substrates. A blade is dragged through the circular or rectangular samples at ...
• #### Development of an awareness-based intervention to enhance quality of life in severe dementia: trial platform ﻿

(2010-06-25)
Abstract Background Quality of residential care for people with severe dementia is in urgent need of improvement. One reason for this may be the assumption that people with severe dementia are unaware of what is happening ...
• #### Development of an integrated genome informatics, data management and workflow infrastructure: A toolbox for the study of complex disease genetics ﻿

(2004-01-01)
Abstract The genetic dissection of complex disease remains a significant challenge. Sample-tracking and the recording, processing and storage of high-throughput laboratory data with public domain data, require integration ...
• #### Development of an open technology sensor suite for assisted living: a student-led research project ﻿

(Royal Society Publishing, 2016-06-17)
Many countries have a rapidly ageing population, placing strain on health services and creating a growing market for assistive technology for older people. We have, through a student-led, 12-week project for 10 students ...
• #### Development of assessment toolkits for improving the diagnosis of the Lewy body dementias: Feasibility study within the DIAMOND Lewy study ﻿

(Wiley, 2016-01-01)
$\textbf{Objective:}$ The Lewy body dementias (LBD, dementia with Lewy bodies and Parkinson's disease dementia) are the second most common cause of neurodegenerative dementia but remain under-recognised, with long delays ...