Theses - Medicine: Recent submissions
Now showing items 1-4 of 127
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Visualisation of innate immune signalling complexes in cells by cryo-electron tomography
Innate immune signalling is a vital immune response to various infections and cell damage. A common feature of innate signalling complexes is forming a signalling platform through oligomerisation in cells. RIG-I-like ... -
Applying at scale genomic and phenotypic approaches to study pathogens linked to nosocomial transmission and disease
Infectious diseases continue to pose major threats to human health. This manifests in different ways, from the incessant rise of antimicrobial resistance, to seasonal epidemics of respiratory viruses and global pandemics, ... -
Immune Transcriptome and B cell receptor repertoire in COVID-19
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) resulting in Coronavirus disease 2019 (COVID-19) was declared by the World Health Organization a global pandemic on March 11, 2020. SARS-CoV-2 primarily infects ... -
Ionic Control of Porin Permeability
Porins are transmembrane proteins within the outer membrane of gram-negative bacteria that allow nutrients, and small molecules, including antibiotics, to enter the cell. Electrophysiological studies on porins reconstituted ...
