### Recent Submissions

• #### Glycaemic control in pregnancies complicated by type 1 diabetes ﻿

(2018-07-20)
Type 1 diabetes in pregnancy is associated with higher rates of maternal and infant complications. The complications are associated with maternal hyperglycaemia. Thus, the main goal of treatment for these women is to ...
• #### Characterisation of human metabolism in physiological and pathophysiological states ﻿

(2018-07-21)
The aim of this thesis was to describe the relationships between energy expenditure and body composition in healthy adults and children and in patients with metabolic disorders. In a healthy population resting energy ...
• #### Hypothalamic Nutrient Sensing ﻿

Nutrient sensing neurons are unique in coupling changes in the concentration of nutrients to changes in neuronal activity. These neurons typically exist in regions of the brain where the blood brain barrier is fenestrated, ...
• #### Mechanistic Investigation of Genotype-Phenotype Correlations in PIK3R1-Related Diseases ﻿

The PIK3R1 gene encodes three proteins - p85$\alpha$, p50$\alpha$ and p55$\alpha$ - that are regulatory subunits of Class IA phosphoinositide 3-kinases (PI3Ks). These regulatory subunits heterodimerise with one of three ...