About this collection

Recent Submissions

  • Characterisation of the AP-3 adaptor-like complex 

    Peden, Andrew Alexander (2000-02-15)
    Clathrin coated vesicles were the first type of coated vesicle to be characterised. The coat consists of two components, clathrin and adaptor (or AP) complexes, the AP-1 complex is associated with the clathrin coated vesicles ...
  • The mechanism of HIV-1 Nef-mediated downregulation of CD4 

    Chaudhuri, Rittik (2010-02-09)
    Nef, an accessory protein of HIV-1, is a critical determinant of viral pathogenicity. The pathogenic effects of Nef are in large part dependent on its ability to decrease the amount of CD4 on the surface of infected cells. ...