Theses - Clinical Biochemistry: Recent submissions
Now showing items 1-4 of 39
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Optimisation of molecular imaging using 11C-methionine PET in the detection of pituitary adenomas
Decision-making in pituitary disease is critically dependent on high-quality imaging of the sella and parasellar region. Magnetic resonance imaging (MRI) is the investigation of choice, and for the majority of patients ... -
Novel functions of N-acetyltransferase 10 (NAT10) in DNA repair and replication with potential implications for premature ageing syndromes
Hutchinson-Gilford Progeria Syndrome (HGPS) is an invariably fatal disease with a range of diverse symptoms that are normally associated with those of advanced age. In recent decades, clinicians and scientists together ... -
Functional validation of human rare missense variants associated with body fat distribution and cardiometabolic risk
Body fat distribution is a predictor of metabolic and cardiovascular disease independent of body mass index (BMI) and is heritable. To understand the genetic determinants of the differences observed in fat distribution in ... -
Structure and function of the R2B adhesive receptor tyrosine phosphatases
Protein tyrosine phosphatases (PTPs) are key regulators of cellular signalling through the control of cellular phosphotyrosine levels. The R2B family of receptor-like PTPs – PTPRK, PTPRU, PTPRM and PTPRT - are well placed ...
